Sodium Pidolate

CAS Number
28874-51-3
EC Number
249-277-1
Abbreviation
PCA

What is Sodium Pidolate?

Sodium Pidolate (CAS 28874-51-3), also known as Sodium Pyroglutamate, is the sodium salt of pyroglutamic acid and a naturally occurring component of the skin's natural moisturizing factor (NMF).

Where is Sodium Pidolate used?

  • Personal care: humectant and moisture-retention agent in moisturizers, serums, and hair conditioners
  • Pharmaceutical: stabilizing excipient in topical preparations and oral formulations where moisture regulation affects shelf life
  • Food and nutrition: flavor enhancer and stabilizer in processed foods, functional beverages, and nutritional supplements
  • Professional skincare actives and amino acid-based treatments target dry or compromised skin conditions.

Good to know: Buyers should confirm grade-specific documentation, including CoA and residual solvent data, at the sourcing stage to ensure compliance with all safety standards.

Other Names (Synonyms)

Sodium pyroglutamate|Sodium (2S)-5-oxopyrrolidine-2-carboxylate|Sodium pca|PCA

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What are the physical properties of Sodium Pidolate?

Melting Point 42 °C
Boiling Point 313.7°C[at 101 325 Pa]
Density 1.45
Color Clear Colorless to Pale Yellow
Form Oil
Water Solubility 613g/L at 20℃
Vapor Pressure 5.4hPa at 20℃
Log P -2.387 (est)
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