Ornithine aspartate

Ornithine aspartate (CAS 3230-94-2), also known as LOLA and marketed under names such as Hepamerz, is a salt formed from two amino acids used primarily in pharmaceutical manufacturing and clinical nutrition.

It functions as a metabolic agent supporting ammonia detoxification pathways, making it a target active ingredient for hepatology-focused drug development and formulation for global suppliers.

In pharmaceutical manufacturing, LOLA is the active substance in infusion solutions and oral granules indicated for hepatic encephalopathy and liver dysfunction, where reducing elevated blood ammonia levels is the primary goal.

Contract formulators and API suppliers source it for finished dosage form development, including sachets, injectables, and oral liquid preparations to meet specific patient needs in clinical settings.

In clinical nutrition products, it is incorporated into specialized medical foods targeting patients with compromised liver function. Cosmetic formulators have also evaluated it as a humectant and pH-buffering agent.

While it is used in skin-conditioning formulations, pharmaceutical applications represent the dominant commercial demand. Ornithine aspartate is supplied as a white crystalline powder for industrial use.

It is available in pharmaceutical-grade specifications aligned with in-house or compendial standards, with purity levels typically at 98% or above to meet API requirements and USP or EP quality.

Bulk quantities are offered for industrial manufacturing, with smaller research-grade quantities available for formulation development. This ensures consistency across various production scales and applications.