Bronopol

CAS Number
52-51-7
EC Number
200-143-0

What is Bronopol?

Bronopol (CAS 52-51-7), also known commercially as beta-Bromo-beta-nitrotrimethyleneglycol and 2-Nitro-2-bromo-1,3-propanediol, is a broad-spectrum antimicrobial active used primarily as a preservative and biocide.

Where is Bronopol used?

  • Personal care and cosmetics: preservative in rinse-off and leave-on formulations including shampoos, lotions, and liquid soaps
  • Industrial water treatment: suppresses bacterial populations
  • Cooling towers and process water circuits: maintains system efficiency
  • Oilfield and metalworking: prevents microbial-induced corrosion and spoilage in drilling fluids and cutting fluid emulsions
  • Pulp, paper, and textile processing: controls slime-forming bacteria that degrade product quality and clog equipment
  • It controls bacterial growth effectively at low concentrations.

Commercial specifications

  • Technical grade for industrial applications; higher-purity grades meeting pharmaceutical and cosmetic manufacturing standards
  • Packaging from kilogram-scale bags to bulk quantities

Other Names (Synonyms)

Bronopolu|beta-Bromo-beta-nitrotrimethyleneglycol|2-Nitro-2-bromo-1,3-propanediol|2-Bromo-2-nitropropane-1,3-diol|2-Bromo-2-nitro-1,3-propanediol|Bronosol|Bronocot|Bronotak

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What are the physical properties of Bronopol?

Melting Point 131.5 °C
Boiling Point 358.0±42.0 °C(Predicted)
Density 1.1 g/cm³
Flash Point 167°C
Appearance off-white crystalline powder
Color White to yellow
Odor odorless
Form Crystals or Crystalline Powder
Water Solubility 25 g/100 mL (22 ºC)
Refractive Index 1.6200 (estimate)
Log P 1.150 (est)

How is Bronopol classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant GHS09· Environmental Hazard GHS06· Toxic GHS02· Flammable GHS08· Health Hazard

Hazard Statements

H228 Flammable solid
H301 Toxic if swallowed
H302 Harmful if swallowed
H310 Fatal in contact with skin

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.

Which trade and regulatory codes apply to Bronopol?

HS Code 29055999
UN Number 3241
ADR Class 4.1
Packing Group III
Storage Class 4.1B - Flammable solid hazardous materials
WGK (Germany) 2
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