Palmitoylethanolamide

Palmitoylethanolamide (CAS 544-31-0), commonly abbreviated as PEA, is a fatty acid amide produced from palmitic acid and ethanolamine. Also known as palmitic acid monoethanolamide.

Where is Palmitoylethanolamide used?

• Pharmaceutical formulations: active ingredient in oral and topical dosage forms
• Personal care: emulsifier and foam stabilizer in cleansing systems, shampoos and skin creams
• Cosmetic formulations: supports emulsification of oil-water systems, reducing the need for additional co-emulsifiers
• Industrial surface treatment: wetting and dispersing agent that improves substrate adhesion and coating uniformity

Good to know: Regulatory-grade purity and consistent particle size are critical sourcing criteria. Micronized and ultramicronized grades differ in particle size distribution and bioavailability profile, a key specification decision for formulators.

Commercial specifications

• Micronized and ultramicronized grades
• Batches meet USP and EP standards