SoleChem

Palmitoylethanolamide

Oils, Fats & Waxes Pharmaceuticals & Healthcare
CAS
544-31-0
EC
208-867-9
Mol. Weight
299.5 g/mol

Description

Palmitoylethanolamide (CAS 544-31-0), commonly abbreviated as PEA, is a fatty acid amide produced from palmitic acid and ethanolamine. Known in industrial contexts as palmitic acid monoethanolamide, it functions as a surface-active agent and emulsifier.

This versatile compound is utilized across pharmaceutical and personal care manufacturing. In pharmaceutical formulations, PEA is incorporated as an active ingredient in oral and topical dosage forms where high purity is required.

Regulatory-grade purity and consistent particle size are critical sourcing criteria for manufacturers. Personal care producers use it as an emulsifier and foam stabilizer in cleansing systems, shampoos, and skin creams.

The material contributes significantly to texture and product stability in various applications. In cosmetic formulations, it supports emulsification of oil-water systems, reducing the need for additional co-emulsifiers.

Industrial surface treatment processes use palmitic acid monoethanolamide as a wetting and dispersing agent. These properties help to improve substrate adhesion and coating uniformity in specialized manufacturing environments.

The product is supplied as a white to off-white powder or waxy solid. Pharmaceutical and nutraceutical applications are served by micronized and ultramicronized grades to meet specific formulation needs.

These grades differ in particle size distribution and bioavailability profile, which is a key specification decision for formulators. Technical and cosmetic grades are also available for non-pharmaceutical applications.

Our supply chain ensures that all batches meet rigorous quality standards such as USP and EP. This ensures reliability for global manufacturers seeking consistent performance in their chemical raw materials.

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Physical Properties

Melting Point 98.5 °C
Boiling Point 461.5±28.0 °C(Predicted)
Density 0.910±0.06 g/cm3(Predicted)
Color White
Form White solid
Water Solubility 4.01mg/L at 20℃
Vapor Pressure 0.45Pa at 20℃
Log P 3.989 at 20℃

Safety & Handling (Learn More)

Danger GHS05 GHS07 GHS09
Hazard Statements
H315 Causes skin irritation
H318 Causes serious eye damage
H411 Toxic to aquatic life with long lasting effects
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P264 Wash … thoroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P332+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 2934.99.4400
UN Number 3077
WGK (Germany) 2

Documentation

Other Names

Palmitoyl-EA|Palmitinsaeure-beta-hydroxyethylamid|Palmitic acid monoethanolamide|Palmitamide MEA|N-Hexadecyl-ethanolamine|N-hexadecanoylethanolamine|N-(2-Hydroxyethyl)palmitamide|N-(2-Hydroxyethyl)hexadecanamide|PEA

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