Ethanesulfonic acid

Ethanesulfonic acid (CAS 594-45-6) is a strong aliphatic sulfonic acid used in pharmaceutical synthesis and biotechnology as a pH regulator, catalyst, and reaction medium component.

Where is Ethanesulfonic acid used?

• Pharmaceutical manufacturing: forms stable acid addition salts with active pharmaceutical ingredients, improving crystallinity, bioavailability, and handling
• Organic synthesis: Brønsted acid catalyst driving esterification, cyclization, and condensation
• Biotechnology: buffering agent in cell culture media and enzyme assay systems
• API purification: solvent modifier or carrier component in chromatographic and extraction processes
• It is a practical alternative to methanesulfonic acid where a slightly longer carbon chain is required.

Good to know: Not to be confused with methanesulfonic acid; a slightly longer carbon chain may be required for solubility or selectivity. Complies with USP, Ph. Eur., BP, EP, and ACS specifications.

Commercial specifications

• Technical and high-purity grades for research and GMP production
• Packaging from laboratory-scale quantities to bulk drums