Triphenylphosphine
CAS Number
603-35-0
EC Number
210-036-0
Abbreviation
TPP
What is Triphenylphosphine?
Triphenylphosphine (CAS 603-35-0), commonly abbreviated as TPP, is a phosphorus-based ligand and reagent.
Where is Triphenylphosphine used?
- Pharmaceutical manufacturing: key reagent in Mitsunobu and Wittig reactions
- Polymer production: processing stabilizer and catalyst precursor in polyester and polyurethane systems
- Printing ink and packaging: photoinitiator components and stabilizers in UV-curable coatings
- Specialty catalysts: ligand for palladium, rhodium, and other transition metals in cross-coupling reactions
- It enables stereoselective synthesis of active pharmaceutical ingredients at scale.
Commercial specifications
- High-purity grades meeting pharmaceutical manufacturing requirements
- Packaging from kilogram-scale bags to bulk drums
Other Names (Synonyms)
Phosphine, triphenyl-|PP 360|TPP
What are the physical properties of Triphenylphosphine?
Melting Point 80.5 °C
Boiling Point >360 °C
Density 1.075 g/cm³ @ Temp: 80 °C
Flash Point 181 °C
Appearance White, crystalline solid. Insoluble inwater; slightly soluble in alcohol; soluble in benzene, acetone, carbon tetrachloride. Combustible.
Color White
Odor odorless
Form Crystals, Crystalline Powder or Flakes
Water Solubility Insoluble
Vapor Pressure 5 mm Hg ( 20 °C)
Refractive Index 1.6358
How is Triphenylphosphine classified and handled safely? Learn More
Danger
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
Which trade and regulatory codes apply to Triphenylphosphine?
HS Code 29310095
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
WGK (Germany) 2