Triphenylphosphine
Description
Triphenylphosphine (CAS 603-35-0), commonly abbreviated as TPP, is a phosphorus-based ligand and reagent used across pharmaceutical synthesis, polymer stabilization, and specialty chemical manufacturing.
It functions primarily as a catalyst component, reducing agent, and stabilizer precursor in demanding industrial processes. In pharmaceutical manufacturing, TPP is a key reagent in Mitsunobu and Wittig reactions.
This material enables stereoselective synthesis of active pharmaceutical ingredients at scale. Polymer producers incorporate it as a processing stabilizer and catalyst precursor in polyester and polyurethane systems.
In these applications, it controls oxidative degradation during high-temperature compounding. Printing ink and packaging formulators use TPP-derived systems as photoinitiator components and stabilizers.
These additives extend the service life of UV-curable coatings. In specialty catalyst systems, it acts as a ligand for palladium, rhodium, and other transition metals, supporting cross-coupling reactions.
Such reactions are critical to fine chemical production. Triphenylphosphine is supplied as a white crystalline powder and is available in technical grade for industrial catalyst and polymer applications.
It is also offered in high-purity grades meeting pharmaceutical manufacturing requirements. Packaging options typically range from kilogram-scale bags to bulk drum quantities to suit various needs.
These formats support both R&D and production-scale procurement. Our logistics network ensures reliable delivery of this essential phosphorus-based reagent for your specific industrial requirements.
Physical Properties
| Melting Point | 80.5 °C |
| Boiling Point | >360 °C |
| Density | 1.075 g/cm³ @ Temp: 80 °C |
| Flash Point | 181 °C |
| Appearance | White, crystalline solid. Insoluble inwater; slightly soluble in alcohol; soluble in benzene, acetone, carbon tetrachloride. Combustible. |
| Color | White |
| Odor | odorless |
| Form | Crystals, Crystalline Powder or Flakes |
| Water Solubility | Insoluble |
| Vapor Pressure | 5 mm Hg ( 20 °C) |
| Refractive Index | 1.6358 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29310095 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 2 |
Documentation
Other Names
Phosphine, triphenyl-|PP 360|TPP
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