Flavin Adenine Dinucleotide Disodium (FAD)

Flavin Adenine Dinucleotide Disodium (FAD) (CAS 84366-81-4) is the disodium salt form of flavin adenine dinucleotide, a biologically active coenzyme belonging to the Vitamin B2 family. As a redox-active cofactor, FAD participates in a broad range of enzymatic oxidation-reduction reactions, making it a technically relevant ingredient across pharmaceutical, nutraceutical, and personal care formulations. In pharmaceutical and healthcare applications, FAD disodium is valued for its role as a bioavailable Vitamin B2 derivative suitable for use in injectable preparations, specialised clinical formulations, and active pharmaceutical ingredient (API) blends. Manufacturers working to pharmacopoeial standards should confirm applicable Ph. Eur. or USP monograph alignment with their specific grade upon enquiry, as specifications may vary by supplier lot.

Within the nutraceutical and dietary supplement sector, Vitamin B2 carries a well-established set of authorised EU health claims under Regulation (EC) No 432/2012. These include contribution to normal energy-yielding metabolism, normal functioning of the nervous system, maintenance of normal skin and vision, normal iron metabolism, reduction of tiredness and fatigue, and protection of cells from oxidative stress. Formulators should note that the FAD disodium form is not listed in Annex II of Directive 2002/46/EC as an authorised supplement source in the EU; regulatory suitability for finished supplement products should be verified against applicable national and supranational requirements. In personal care and cosmetics, FAD disodium functions as an antioxidant and cell-conditioning agent. Its affinity for biological redox systems supports its inclusion in premium skincare serums, topical treatments, and anti-ageing formulations where ingredient efficacy is a key differentiator for finished-product positioning.

FAD disodium is typically available in powder form, with purity specifications commonly at or above 95% by assay. Grades suited to cell culture, cosmetic, and pharmaceutical research applications are available, and buyers are encouraged to specify their end-use requirements to ensure the appropriate certificate of analysis and documentation package is supplied. Recommended storage conditions are generally at or below −20 °C to maintain coenzyme integrity over shelf life. SoleChem supplies this material in small research quantities as well as in larger bulk consignments, with packaging options including 1–5 kg units for pilot and development batches and 25 kg drums for commercial-scale procurement.

Full technical documentation — including certificates of analysis, safety data sheets, and regulatory support files — is available on request. Contact SoleChem's technical sales team to discuss grade suitability, lead times, and supply volumes for your specific application.