Hyaluronic acid

CAS Number
9004-61-9
EC Number
232-678-0
Abbreviation
HA

What is Hyaluronic acid?

Hyaluronic acid (CAS 9004-61-9), also known as HA, is a naturally derived polysaccharide used in cosmetic, pharmaceutical and biotech manufacturing. Also marketed as Luronit and Sepracoat.

Where is Hyaluronic acid used?

  • Skincare and topical cosmetics: humectant in serums, creams and sheet masks for surface hydration across molecular weight grades
  • Pharmaceutical: viscoelastic agent in ophthalmic solutions and carrier matrix in injectable joint therapy formulations
  • Wound care and medical device coatings: biocompatible hydrating layer for tissue contact
  • Biotech and life science: scaffold component in cell culture media and tissue engineering substrates
  • It acts as a viscosity modifier in formulations requiring sustained moisture retention and texture control.

Good to know: Sodium hyaluronate is the most commercially prevalent salt form. Standard grades include cosmetic, food-grade and pharmaceutical-grade (USP/EP), with molecular weight ranges specified to match application requirements.

Commercial specifications

  • Molecular weight ranges: low, medium and high
  • Bulk quantities and smaller research and pilot-scale packaging

Other Names (Synonyms)

Mucoitin|Luronit|Sepracoat|HA

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What are the physical properties of Hyaluronic acid?

Color White
Odor Odorless
Form Lyophilized Powder
Water Solubility Soluble in water.
Log P -6.623 (est)

Which trade and regulatory codes apply to Hyaluronic acid?

WGK (Germany) 3
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