Sodium hyaluronate
Description
Sodium hyaluronate (CAS 9067-32-7), the sodium salt form of hyaluronic acid (HA), is a high-molecular-weight polysaccharide sourced from microbial fermentation or animal-derived raw materials.
It functions as a humectant, film-former, and viscosity modifier across cosmetic, pharmaceutical, and biomedical formulations. Healon is a recognized trade name in ophthalmic applications.
In skincare and topical formulations, HA binds moisture to the skin surface and improves product texture in serums, creams, and sheet masks. Molecular weight selection determines depth of hydration.
Ophthalmic surgeons and device manufacturers use pharmaceutical-grade material as a viscoelastic agent in cataract procedures and as a base for eye drop formulations targeting dry eye syndrome.
Intra-articular injectable grades are used in viscosupplementation therapies for osteoarthritis, where it acts as a synovial fluid supplement. In biotechnology, it is used as a scaffold material.
Sodium hyaluronate is supplied as a white to off-white powder in a range of molecular weights, typically categorized as low, medium, and high. Available grades include USP and Ph. Eur.
Food-grade and cosmetic-grade materials are also widely stocked for various industrial needs. Molecular weight and purity specifications are the primary procurement differentiators across end-use segments.
Physical Properties
| Melting Point | >209°C (dec.) |
| Appearance | solid |
| Color | White to cream |
| Form | Powder |
| Water Solubility | SOLUBLE |
| pH | pH(2g/l,25℃) : 5.5~7.5 |
| Log P | -6.623 (est) |
Trade & Regulatory
| HS Code | 39139000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
Hyaluronic acid sodium salt|Hyaluronic acid|Healon|SPH|Hyladerm|Hyaluronate Acid|HA
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