Polyglutamic acid

Polyglutamic acid (CAS 25513-46-6), commonly abbreviated as PLG, is a naturally derived biopolymer produced through microbial fermentation of glutamic acid. It functions as a high-performance humectant and rheology modifier across cosmetic, food, pharmaceutical, and biotechnology applications.

In skincare and cosmetic formulations, PLG outperforms hyaluronic acid in moisture retention capacity, making it a sought-after active in serums, creams, and hydrating masks. Food manufacturers incorporate it as a texture modifier and water-binding agent.

This ingredient is ideal for products where clean-label, fermentation-derived ingredients are preferred. In pharmaceutical drug delivery research, PLG serves as a biodegradable carrier matrix for controlled-release systems and peptide conjugation.

Biotechnology applications include use as a scaffold material in cell culture media and as a chelating agent in fermentation process optimization. Polyglutamic acid is supplied as a white to off-white powder or as an aqueous solution.

The material is available at varying concentrations to suit specific industrial needs. Cosmetic-grade and food-grade specifications are the most commercially prevalent, with molecular weight ranges specified to match application viscosity.

Low, medium, or high MW options are provided to ensure optimal absorption requirements. Pharmaceutical and research-grade material is available for procurement where documented purity and batch traceability are required.

Our supply chain ensures that all batches meet rigorous quality standards for global distribution. We provide comprehensive documentation for regulatory compliance in diverse markets, ensuring consistent performance in every formulation.