Diethylphenylamine-borane

CAS Number
13289-97-9
EC Number
236-305-2

What is Diethylphenylamine-borane?

Diethylphenylamine-borane (CAS 13289-97-9), also known as N,N-diethylanilineborane, is a selective organoboron reducing agent used in synthetic chemistry and pharmaceutical manufacturing.

Where is Diethylphenylamine-borane used?

  • Pharmaceutical intermediates: reduces imines, oximes and carbonyl compounds with high chemoselectivity
  • Supports production of chiral amines and active pharmaceutical ingredient precursors
  • Industrial cleaning and surface treatment: catalyst or initiator in polymerization systems
  • Biotechnology research: reductive amination for labeling, conjugation and biomolecule modification
  • Organometallic chemistry: catalyst precursor
  • It delivers controlled hydride reduction under mild conditions.

Good to know: Offers greater selectivity than many conventional borohydride reagents. Its amine-borane structure enables activation under specific reaction conditions.

Commercial specifications

  • Liquid or low-melting solid, depending on purity and handling conditions
  • Research and commercial quantities
  • Technical and high-purity grades
  • Packaging from small-scale laboratory quantities; bulk supply for process-scale synthesis

Other Names (Synonyms)

N,n-diethylanilineborane|Boron, (n,n-diethylbenzenamine)trihydro-, (T-4)-|(T-4)-(N,N-Diethylbenzenamine)trihydroboron|Borane-n,n-diethylaniline

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What are the physical properties of Diethylphenylamine-borane?

Melting Point −30-−27 °C(lit.)
Density 0.917 g/mL at 25 °C(lit.)
Flash Point 70 °F
Appearance clear colorless to amber liquid
Color Clear colorless to yellow
Form Liquid
Water Solubility MAY DECOMPOSE
Refractive Index 1.5245-1.5265

How is Diethylphenylamine-borane classified and handled safely? Learn More

Danger
GHS02· Flammable GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard

Hazard Statements

H225 Highly Flammable liquid and vapor
H260 In contact with water releases flammable gases which may ignite spontaneously
H261 In contact with water releases flammable gas
H301 Toxic if swallowed

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P223 Do not allow contact with water.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Which trade and regulatory codes apply to Diethylphenylamine-borane?

HS Code 29299090
UN Number 3398
ADR Class 4.3
Packing Group II
WGK (Germany) 3
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