Diethylphenylamine-borane

Diethylphenylamine-borane (CAS 13289-97-9), also known as N,N-diethylanilineborane, is a selective organoboron reducing agent used in synthetic chemistry and pharmaceutical manufacturing. It delivers controlled hydride reduction under mild conditions. This reagent offers greater selectivity than many conventional borohydride reagents. In pharmaceutical intermediate synthesis, it reduces imines, oximes, and carbonyl compounds with high chemoselectivity.

It supports the production of chiral amines and active pharmaceutical ingredient precursors. Industrial cleaning and surface treatment formulations use it as a catalyst or initiator in polymerization systems. In biotechnology research, it supports reductive amination protocols for labeling, conjugation, and biomolecule modification workflows. It also functions as a catalyst precursor in organometallic chemistry.

Its amine-borane structure enables activation under specific reaction conditions. Diethylphenylamine-borane is typically supplied as a liquid or low-melting solid, depending on purity and handling conditions. It is available in research and commercial quantities, with technical and high-purity grades suited to pharmaceutical and specialty chemical applications. Packaging ranges from small-scale laboratory quantities.

Bulk supply is available for process-scale synthesis. The material is handled according to strict safety protocols to ensure stability and performance in sensitive chemical transformations and industrial processes.