Pyridine-borane

CAS Number
110-51-0
EC Number
203-773-4

What is Pyridine-borane?

Pyridine-borane (CAS 110-51-0) is a stabilized borane complex that delivers controlled hydride-reducing activity under mild conditions.

Where is Pyridine-borane used?

  • Synthetic chemistry: selective reducing agent
  • Pharmaceutical manufacturing: reduces imines and iminium ions in reductive amination
  • Electronics: electroless plating baths and surface treatment
  • Biotechnology: reductive amination of biomolecules including proteins, peptides, and oligosaccharides
  • It also serves synthetic chemistry workflows requiring mild reduction of aldehydes and ketones without over-reduction.

Good to know: Offers greater handling safety and solution stability than free borane reagents. Selectivity and aqueous compatibility are priorities in these applications.

Commercial specifications

  • Colorless to pale yellow liquid, typically around 8 M in solution
  • Research quantities through to multi-kilogram lots
  • Technical and high-purity grades
  • Purity specifications commonly at 97% or above

Other Names (Synonyms)

Pyridine-borane (1:1)|Trihydro(pyridine)boron|Borane-pyridine (1:1)|8JXE4C7UEX|RefChem:177566|Boron, trihydro(pyridine)-, (T-4)-

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What are the physical properties of Pyridine-borane?

Melting Point 46-47 °C
Boiling Point 102 °C (0.37505 mmHg)
Density 0.929 g/mL at 20 °C
Flash Point 70 °F
Appearance clear to slightly hazy colorless to amber liquid
Color Clear to slightly hazy colorless to amber
Form Liquid
Water Solubility reacts slowly
Refractive Index n 20/D 1.532(lit.)

How is Pyridine-borane classified and handled safely? Learn More

Danger
GHS02· Flammable GHS06· Toxic

Hazard Statements

H225 Highly Flammable liquid and vapor
H301 Toxic if swallowed
H310 Fatal in contact with skin
H311 Toxic in contact with skin
H330 Fatal if inhaled
H310+H330 Fatal in contact with skin or if inhaled

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Which trade and regulatory codes apply to Pyridine-borane?

HS Code 29333990
UN Number 1992
ADR Class 3
Packing Group II
WGK (Germany) 2
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