9-Borabicyclononane

9-Borabicyclononane (CAS 280-64-8), commercially its stable dimer 9-borabicyclo[3.3.1]nonane dimer, is a selective hydroboration reagent used in synthetic chemistry.

Where is 9-Borabicyclononane used?

• Pharmaceutical manufacturing: enantiomerically enriched intermediates for active pharmaceutical ingredients where stereochemical control is critical
• Suzuki–Miyaura cross-coupling: boron source for carbon–carbon bonds in drug candidates and fine chemicals
• Biotechnology and life sciences: preparation of labeled compounds and probe molecules for biological assays and diagnostic testing
• Industrial cleaning and specialty chemicals: catalyst precursor in boron-mediated reaction sequences requiring high regioselectivity
• It enables precise, stereoselective addition of boron to alkenes for chiral intermediates in complex molecule synthesis.

Commercial specifications

• Solid dimer or stabilized solutions in tetrahydrofuran or other anhydrous solvents
• Solution grades typically 0.5 M and 1.0 M
• Research, pilot, and commercial scale