Bispinacolatodiborane

CAS Number
73183-34-3
EC Number
615-925-0

What is Bispinacolatodiborane?

Bispinacolatodiborane (CAS 73183-34-3), also known as B2pin2, is a diboron reagent used as a borylation source in synthetic chemistry and pharmaceutical manufacturing.

Where is Bispinacolatodiborane used?

  • Pharmaceutical synthesis: reagent for palladium-catalyzed Miyaura borylation, converting aryl and vinyl halides into pinacol boronate esters
  • API production: intermediates for Suzuki–Miyaura cross-coupling
  • Specialty polymers: introduction of boron-functional groups for controlled crosslinking and stimuli-responsive material design
  • Fine chemical and agrochemical synthesis: preparation of borylated building blocks
  • Textile and paper sectors: surface-functionalizing agents derived from boronate chemistry
  • It delivers two pinacolboronate ester units in a single reagent, enabling introduction of boronic ester groups into organic molecules without air-sensitive handling.

Commercial specifications

  • Purity grades typically 97% to 99%+
  • Research quantities through to multi-kilogram lots

Other Names (Synonyms)

Bis(pinacolate)diborane|4,4,5,5-tetramethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3,2-dioxaborolane|Bis(pinacolato)diborane

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What are the physical properties of Bispinacolatodiborane?

Melting Point 139-140 °C
Boiling Point 222.6±7.0 °C(Predicted)
Density 0.98
Appearance white crystal powder
Color White
Form Powder or Platelets
Water Solubility Soluble in tetrahydrofuran, dichloromethane, toluene, hexane and heptane. Insoluble in water.

How is Bispinacolatodiborane classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H315 Causes skin irritation
H317 May cause an allergic skin reaction

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Which trade and regulatory codes apply to Bispinacolatodiborane?

HS Code 29209090
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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