4-Hydroxy-TEMPO

CAS Number
2226-96-2
EC Number
218-760-9
Chemical Formula
C9H18NO2
Molecular Weight
172.24 g/mol
Abbreviation
TEMPOL

Description

4-Hydroxy-TEMPO (CAS 2226-96-2), commercially known as TEMPOL, is a stable nitroxide radical used across polymer, pharmaceutical, and personal care manufacturing. It functions primarily as a polymerization inhibitor and radical scavenger. This chemical acts as a process stabilizer, preventing premature crosslinking or degradation during production and storage. In polymer and resin manufacturing, it inhibits unwanted radical polymerization in monomer streams.

By protecting product integrity during transport and storage, it ensures high-quality outcomes. Pharmaceutical manufacturers use it as a controlled radical mediator in active ingredient synthesis and as an antioxidant stabilizer. In personal care, it is incorporated into formulations requiring oxidative stability. This is particularly important where free radical chain reactions would compromise shelf life or efficacy in the final consumer product.

TEMPOL also serves as a catalyst in selective oxidation reactions, including the conversion of primary alcohols to aldehydes. This functionality is essential in fine chemical and API synthesis workflows for modern medicine. The product is supplied as a crystalline solid, typically as an orange to red-orange powder or granules. It is available in technical and high-purity grades, with purity specifications commonly ranging from 97% to 99%+.

These grades are suitable for research, pharmaceutical, and industrial applications. Packaging options range from small laboratory quantities to bulk industrial supply, depending on specific application requirements and scale.

Other Names (Synonyms)

Tempol

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Contact us for supply of 4-Hydroxy-TEMPO

Request Quote

Physical Properties

Melting Point 71-73 °C
Boiling Point 302.58°C (rough estimate)
Density 1.0402 (rough estimate)
Flash Point 146°(295°F)
Appearance solid
Color Orange
Form Crystals or Crystalline Powder
Water Solubility soluble
Vapor Pressure 0.025Pa at 20℃
Refractive Index 1.4350 (estimate)
pH 8.2 (20g/l, H2O, 20℃)
Log P 0.56 at 25℃

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 H302
H315 H315
H318 H318
H319 H319

Precautionary Statements

P260 P260
P261 P261
P264 P264
P270 P270

Trade & Regulatory

HS Code 29333999
Storage Class 11 - Combustible Solids
WGK (Germany) 1
Call Request Quote