Flavors & Fragrances
REACH
2,4,5-Trimethyl-3-oxazoline
CAS Number
22694-96-8
EC Number
607-131-8
FEMA Number
FEMA 3525
Industries: Food & Nutrition
What is 2,4,5-Trimethyl-3-oxazoline?
2,4,5-Trimethyl-3-oxazoline (CAS 22694-96-8) is a heterocyclic oxazoline compound used as a specialty aroma chemical and pharmaceutical building block. FEMA No. 3525.
Where is 2,4,5-Trimethyl-3-oxazoline used?
- Flavor formulation: roasted, nutty odor profile
- Synthetic chemistry: reactive oxazoline ring as intermediate
- Food, beverage and tobacco: roasted and cocoa-like notes with controlled dosing
- Pharmaceutical and biotech research: oxazoline scaffold as synthetic intermediate for heterocyclic APIs and research compounds
- Asymmetric catalysis: preparation of chiral auxiliaries and ligands
- Contract manufacturers evaluate it for ring-opening reactivity.
Commercial specifications
- High purity levels for flavor and pharmaceutical research
- Packaging from small laboratory quantities to larger industrial flavor production volumes
Other Names (Synonyms)
2,5-Dihydro-2,4,5-trimethyloxazole|3-Oxazoline, 2,4,5-trimethyl-|Oxazole, 2,5-dihydro-2,4,5-trimethyl-|peanut oxazole|2,4,5-trimethyl-delta-3-oxazoline|PEANUT FLAVOR
What are the physical properties of 2,4,5-Trimethyl-3-oxazoline?
Boiling Point 45-47°C 12mm
Density 0,919 g/cm 3
Flash Point 45-47°C/12mm
Appearance Yellow-orange liquid; powerful, musty, nut-like odor. Soluble in alc, propylene glycol,water; insoluble in fixed oils.
Odor at 0.10 % in dipropylene glycol. musty nutty vegetable cocoa nut skin bread crust phenolic woody
Form liquid
Water Solubility Soluble in alcohol, fixed oils. Insoluble in water.
Log P 1.72
How is 2,4,5-Trimethyl-3-oxazoline classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Which trade and regulatory codes apply to 2,4,5-Trimethyl-3-oxazoline?
Storage Class 10 - Combustible liquids
WGK (Germany) 3