n-octyl pyrrolidone

CAS Number
2687-94-7
EC Number
403-700-8
Abbreviation
NOP

What is n-octyl pyrrolidone?

N-Octyl Pyrrolidone (CAS 2687-94-7), commonly abbreviated as NOP, is a high-boiling, low-volatility pyrrolidone solvent used in pharmaceutical, coatings, and personal care manufacturing.

Where is n-octyl pyrrolidone used?

  • Coatings and adhesives: improves pigment dispersion and substrate wetting, enabling more uniform film formation on difficult surfaces including plastics and metals
  • Personal care: solvent and penetration enhancer in topical products such as hair treatments
  • Skin conditioners: aids active ingredient delivery
  • Pharmaceutical manufacturing: supports drug solubilization and membrane permeation in transdermal and topical dosage forms
  • Industrial cleaning and agrochemical formulations: emulsification and surface-modification properties that improve active distribution and contact efficiency
  • It functions as a solvent, wetting agent, and dispersant where conventional solvents present regulatory or performance limitations.

Good to know: Buyers should confirm purity specifications and regulatory compliance documentation when sourcing for regulated end markets; REACH registration status is essential for compliance.

Commercial specifications

  • Technical-grade material is the primary commercial form for most industrial and chemical processing needs
  • High-purity grades are available for pharmaceutical and personal care applications

Other Names (Synonyms)

N-Octyl-2-pyrrolidone|1-Octyl-2-pyrrolidinone|1-Octyl-2-pyrrolidone|2-Pyrrolidinone, 1-octyl-|n-(n-octyl)-2-pyrrolidone|RefChem:828515|Surfadone LP 100|NOP

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What are the physical properties of n-octyl pyrrolidone?

Melting Point -25 °C
Boiling Point 170-172 °C
Density 0.91845 g/cm³ @ Temp: 25 °C
Flash Point >230 °F
Color Colorless to Yellow
Form clear liquid
Water Solubility 1.14-1.25g/L at 20℃
Vapor Pressure 0.03-0.08Pa at 20℃
Refractive Index n 20/D 1.465(lit.)
Log P 4.15 at 20℃

How is n-octyl pyrrolidone classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS09· Environmental Hazard

Hazard Statements

H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to n-octyl pyrrolidone?

HS Code 29339900
UN Number 3267
ADR Class 8
Packing Group II
WGK (Germany) 2
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