n-octyl pyrrolidone
Description
N-Octyl Pyrrolidone (CAS 2687-94-7), commonly abbreviated as NOP, is a high-boiling, low-volatility pyrrolidone solvent used across pharmaceutical, coatings, and personal care manufacturing.
It functions as a solvent, wetting agent, and dispersant where conventional solvents present regulatory or performance limitations. In coatings and adhesives, NOP improves pigment dispersion and substrate wetting.
This enables more uniform film formation on difficult surfaces including plastics and metals. Personal care formulators use it as a solvent and penetration enhancer in topical products such as hair treatments.
In skin conditioners, it aids active ingredient delivery. In pharmaceutical manufacturing, it supports drug solubilization and membrane permeation in transdermal and topical dosage forms.
Industrial cleaning and agrochemical formulations rely on NOP's emulsification and surface-modification properties. These characteristics improve active distribution and contact efficiency across various applications.
N-Octyl Pyrrolidone is supplied as a clear liquid in standard drum and IBC quantities. Technical-grade material is the primary commercial form for most industrial and chemical processing needs.
High-purity grades are available for pharmaceutical and personal care applications. Buyers should confirm purity specifications and regulatory compliance documentation when sourcing for regulated end markets.
Documentation such as REACH registration status is essential for compliance. This ensures the material meets the necessary safety and quality requirements for global distribution and manufacturing.
Physical Properties
| Melting Point | -25 °C |
| Boiling Point | 170-172 °C |
| Density | 0.91845 g/cm³ @ Temp: 25 °C |
| Flash Point | >230 °F |
| Color | Colorless to Yellow |
| Form | clear liquid |
| Water Solubility | 1.14-1.25g/L at 20℃ |
| Vapor Pressure | 0.03-0.08Pa at 20℃ |
| Refractive Index | n 20/D 1.465(lit.) |
| Log P | 4.15 at 20℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339900 |
| UN Number | 3267 |
| ADR Class | 8 |
| Packing Group | II |
| WGK (Germany) | 2 |
Documentation
Other Names
N-Octyl-2-pyrrolidone|1-Octyl-2-pyrrolidinone|1-Octyl-2-pyrrolidone|2-Pyrrolidinone, 1-octyl-|n-(n-octyl)-2-pyrrolidone|RefChem:828515|Surfadone LP 100|NOP
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