Piperonyl butoxide

CAS Number
51-03-6
EC Number
200-076-7
Abbreviation
PBO

What is Piperonyl butoxide?

Piperonyl butoxide (CAS 51-03-6), commonly abbreviated as PBO, is a synergist used alongside insecticides to enhance their efficacy by inhibiting the enzymes insects use to break down active ingredients.

Where is Piperonyl butoxide used?

  • Agricultural and public health pest control: incorporated into sprays, dusts, and aerosols to increase knockdown speed and residual activity of pyrethrins against a broad range of insects
  • Home care: household insecticide sprays, mosquito coils, and foggers
  • Personal care: lice treatment formulations enhancing permethrin or pyrethrin activity against head lice
  • Professional pest control operators use PBO-containing concentrates for structural treatments where insecticide resistance is a concern.

Good to know: It does not function as a pesticide on its own but boosts the performance of pyrethrin- and pyrethroid-based formulations, allowing lower active ingredient loadings.

Commercial specifications

  • Technical grade: purity 90–95% or higher
  • Refined grades for pharmaceutical and personal care where regulatory compliance requires tighter quality documentation

Other Names (Synonyms)

5-propyl-4-(2,5,8-trioxa-dodecyl)-1,3-benzodioxole|(butylcarbityl)(6-propylpiperonyl)ether|(3,4-methylenedioxy-6-propylbenzyl) (butyl) diethylene glycol ether|2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether|butyl carbitol 6-propylpiperonyl ether|alpha-[2-(2-butoxyethoxy)ethoxy]-4,5-(methylenedioxy)-2-propyltoluene|alpha-(2-(2-n-butoxyethoxy)-ethoxy)-4,5-methylenedioxy-2-propyltoluene|6-propylpiperonyl butyl diethylene glycol ether|PBO

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What are the physical properties of Piperonyl butoxide?

Melting Point <25 °C
Boiling Point 180 °C @ Press: 1 Torr
Density 1.06 g/cm³ @ Temp: 20 °C
Flash Point >230 °F
Appearance Light Yellow Liquid
Color Clear yellow
Odor mild odor or odorless
Form Liquid
Water Solubility <0.1 g/100 mL at 18 ºC
Vapor Pressure 0.02 hPa (60 °C)
Refractive Index n 20/D 1.498(lit.)
Log P 4.750

How is Piperonyl butoxide classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard GHS08· Health Hazard

Hazard Statements

H317 H317
H319 H319
H335 H335
H373 H373
H400 H400
H410 H410

Precautionary Statements

P260 P260
P261 P261
P271 P271
P272 P272

Which trade and regulatory codes apply to Piperonyl butoxide?

HS Code 29329990
UN Number 3082
ADR Class 9
Packing Group III
Storage Class 10 - Combustible liquids
WGK (Germany) 3
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