20-Hydroxyecdysone

CAS Number
5289-74-7
EC Number
811-097-1
Chemical Formula
C27H44O7
Molecular Weight
480.6 g/mol
Abbreviation
20E

Description

20-Hydroxyecdysone (CAS 5289-74-7), also known as beta-Ecdysone or 20E, is a naturally occurring phytoecdysteroid extracted primarily from plants such as Cyanotis arachnoidea and Leuzea carthamoides. In commercial markets, it functions as a bioactive ingredient targeting protein synthesis support, skin conditioning, and adaptogenic formulation development for various industrial applications.

In sports nutrition and dietary supplements, 20E is incorporated into capsule and powder formulations positioned around muscle recovery and physical performance. Cosmetic formulators use it in anti-aging topicals. Its conditioning activity supports product claims around elasticity and cellular renewal in skin-firming products. Pharmaceutical researchers source 20E as a reference standard for metabolic research.

It is also used as an active ingredient candidate for anabolic research programs. In functional food development, it appears in standardized plant extracts blended into protein powders and energy bars. 20-Hydroxyecdysone is supplied as a white to off-white crystalline powder, both as isolated pure compound and as standardized plant extracts with defined 20E content typically 95%+ by HPLC.

Common supply grades include research-grade, cosmetic-grade, and food/nutraceutical-grade material. Standardized extracts are also available at lower concentrations for direct use in supplement manufacturing.

Other Names (Synonyms)

beta-Ecdysone|THE-7|Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2β,3β,5β,22R)-|5β-Cholest-7-en-6-one, 2β,3β,14,20,22,25-hexahydroxy-, (22R)-|5β-Cholest-7-en-6-one, 2β,3β,14,20,22β,25-hexahydroxy-|(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one|CYANOTIS ARACHNOIDEA ROOT EXTRACT|20E

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 239-240 °C
Boiling Point 498.63°C (rough estimate)
Density 1.0760 (rough estimate)
Color white
Form powder
Refractive Index 1.5800 (estimate)
Log P -0.270 (est)

Safety & Handling (Learn More)

Warning
GHS09· Environmental Hazard

Hazard Statements

H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects

Precautionary Statements

P273 Avoid release to the environment.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code 29372900
WGK (Germany) 2

Documentation

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