Hydroxypropyl cellulose

CAS Number
9004-64-2
EC Number
618-388-0
E Number
E463
Abbreviation
HPC

What is Hydroxypropyl cellulose?

Hydroxypropyl cellulose (CAS 9004-64-2), abbreviated HPC and listed as E463 in food applications, is a water-soluble cellulose ether. Also known as HPC.

Where is Hydroxypropyl cellulose used?

  • Pharmaceutical: binder for tablet wet granulation and film-coating polymer for immediate-release dosage forms
  • Food: stabilizer and emulsifier in processed foods, bakery products and dietary supplements
  • Personal care: viscosity builder and spreadability improver in gels, creams and hair-fixatives
  • Construction: water-retention agent in tile adhesives and cement-based mortars, reducing premature drying during application
  • It gives formulators precise control over viscosity and texture.

Good to know: Standard grades include FCC, USP/NF, Ph. Eur., BP and EP. Bulk supply is typically offered in 25 kg bags, with industrial quantities in fiber drums.

Commercial specifications

  • Low-, medium- and high-viscosity grades
  • 25 kg bags; fiber drums for industrial quantities

Other Names (Synonyms)

lacrisert|hypromellose phthtalate|hydroxypropylmethylcellulose phthalate|Cellulose, 2-hydroxypropyl ether|Hydroxypropyl ether of cellulose|Cellulose hydroxypropyl ether|Oxypropylated cellulose|HPC|E463

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What are the physical properties of Hydroxypropyl cellulose?

Melting Point 155.10 °C
Density 0.50 g/cm³
Appearance white powder
Color White to light cream
Odor Odorless
Form powder
Water Solubility Soluble in polar organic solvents, in water at room temperature.Soluble in water, methyl alcohol, ethyl alcohol and other organic solvents.
Refractive Index 1.5600
pH pH (20g/l, 25℃) : 5.0~7.5

Which trade and regulatory codes apply to Hydroxypropyl cellulose?

HS Code 39129000
WGK (Germany) 1
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