Vitamin E D-Alpha-Tocopherol

CAS Number
59-02-9
EC Number
200-412-2
Chemical Formula
C29H50O2
Molecular Weight
430.7 g/mol
Form
oil
Grade
USP, food

What is Vitamin E D-Alpha-Tocopherol?

Alpha-tocopherol (CAS 59-02-9), also supplied under E307, is the most biologically active form of vitamin E.

Where is Vitamin E D-Alpha-Tocopherol used?

  • Food and nutraceutical manufacturing: stabilizer of oils and fats
  • Pharmaceutical formulations: active ingredient and functional excipient in soft gel capsules, emulsions, and parenteral preparations, protecting lipid-based drug delivery systems
  • Personal care: stabilizer of emollients and carrier oils in creams, serums, and suncare products, supporting UV-induced oxidation control
  • Plastics and polymer processing: non-phenolic antioxidant stabilizer for polyolefins and elastomers during high-temperature compounding
  • It prevents oxidative degradation in lipid-containing systems, extending shelf life and protecting sensitive ingredients from rancidity and free radical damage.

Good to know: Natural grades command a premium in food and pharma procurement. Food-grade purity is typically specified at 96% or higher.

Commercial specifications

  • Natural and synthetic forms
  • USP, Ph. Eur., and FCC grades
  • Bulk supply in drums or IBCs; concentrated mixed tocopherol blends available

Other Names (Synonyms)

alpha-tocopherol|α-Tocopherol|Eprolin|E-Vimin|d-α-tocopherol|d-alpha-tocopherol|Aquasol E|5,7,8-Trimethyltocol|(R,R,R)-α-tocopherol|E307

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What are the physical properties of Vitamin E D-Alpha-Tocopherol?

Melting Point 2-3 °C
Boiling Point 210 °C @ Press: 0.1 Torr
Density 0.95 g/mL at 25 °C(lit.)
Flash Point 253 °C
Appearance light yellow liquid
Color clear yellow
Odor lt. yel. to red visc. oil, nearly odorless
Form oil
Water Solubility INSOLUBLE
Refractive Index n 20/D 1.505(lit.)
Log P 10.962 (est)

How is Vitamin E D-Alpha-Tocopherol classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H317 May cause an allergic skin reaction

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P321 Specific treatment (see … on this label).

Which trade and regulatory codes apply to Vitamin E D-Alpha-Tocopherol?

HS Code 29362800
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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