4-butylresorcinol

4-Butylresorcinol (CAS 18979-61-8), commercially recognized as Rucinol, is a synthetic depigmentation active used in cosmetic and pharmaceutical formulations. It inhibits tyrosinase and peroxidase enzymes involved in melanin synthesis. This makes it a targeted ingredient for skin-brightening and hyperpigmentation correction products. In premium skincare, it is formulated into serums, creams, and spot treatments targeting melasma and age spots.

It is often used at concentrations between 0.1% and 1% for post-inflammatory hyperpigmentation. Pharmaceutical topical preparations use it as an active ingredient in prescription and OTC depigmenting products. Regulatory-grade purity is required for these applications to ensure safety and efficacy. Its antioxidant activity also supports use as a stabilizer in formulations where oxidative degradation is a concern.

Some specialty formulations incorporate it for its mild preservative-boosting effect alongside primary systems. 4-Butylresorcinol is supplied as a white to off-white crystalline powder for industrial use. It is available in cosmetic-grade and pharmaceutical-grade specifications. High-purity grades, typically ≥98% or ≥99% by HPLC, are standard for active cosmetic ingredient supply chains.

Packaging ranges from small quantities for R&D sampling to kilogram-scale lots for commercial batches. This ensures flexibility for both laboratory development and large-scale manufacturing needs.