Disodium 5'-inosinate

Disodium 5'-inosinate (CAS 4691-65-0), also known as E631 and IMP-Na2, is a nucleotide-based flavor enhancer derived from inosine monophosphate.

Where is Disodium 5'-inosinate used?

• Food systems: amplifies savory, umami taste perception
• Seasoning powders, instant noodles, soups and snack coatings: synergistic umami blends with monosodium glutamate and disodium guanylate, often called I+G mixtures
• Processed meat: reinforces meaty flavor profiles
• Savory sauces, bouillon cubes and ready meals: flavor depth
• Oral care and cosmetic formulations: sensory or conditioning purposes
• It allows reduced salt content without sacrificing taste intensity.
• Functions as an emollient, humectant and skin conditioning agent in cosmetic products.
• Used as a certified pharmaceutical reference material for quality control and calibration via chromatographic methods.

Good to know: Typically functions at low use levels, cost-effective relative to glutamates alone. Food-grade is the standard commercial specification, with FCC-compliant material available.

Formulation notes

• Flavor-enhancing power is about 50% that of disodium guanylate.
• A mixture of 98% monosodium glutamate and 2% E635 has four times the flavour-enhancing power of monosodium glutamate alone.

Typical specification

• Shows significant umami synergy with MSG at a ratio of 1:7.
• Available in grades conforming to BP, USP, FCC and EU standards.
• Stable at 100 °C and will not decompose until the temperature reaches about 230 °C.

Regulatory status

• May be added to permitted finished products subject to the relevant restrictions under the Turkish Food Codex regulations on food additives and vertical communiqués.
• The food additive must be manufactured and purified so that it contains no more than 150 ppm of soluble barium, in the form of the disodium inosinate compound with seven and a half molecules of water of crystallisation.
• Its safety when used as a food additive has been approved by the US FDA, EFSA, JECFA and other authorities.

Storage, packaging and handling

• Should be stored in a dry and cool place in a closed container.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.