Riboflavin tetrabutyrate
Description
Riboflavin tetrabutyrate (CAS 752-56-7), also known as Vitamin B2 tetrabutyrate and marketed under the trade name Hibon, is a lipophilic ester form of riboflavin developed to overcome poor oil solubility.
This specialized compound addresses the light sensitivity that limits standard riboflavin in certain delivery systems. Its fat-soluble profile makes it suitable for formulations where conventional riboflavin cannot be effectively incorporated.
In pharmaceutical and nutraceutical manufacturing, it is used in oil-based capsule formulations and lipid delivery systems. This is particularly useful where enhanced bioavailability of B2 is a primary formulation objective.
Feed premix producers use it to fortify fat-soluble vitamin blends for livestock and aquaculture. It remains stable through pelleting and extrusion processes, ensuring nutritional integrity in the final feed product.
In food applications, it functions as an antioxidant and stabilizer in fat-containing matrices such as edible oils and fat-based spreads. Cosmetic formulators also incorporate it into oil-phase systems.
The product provides a stable, non-discoloring B2 source for topical applications. Riboflavin tetrabutyrate is supplied as a yellow to orange powder or crystalline solid for various industrial uses.
It is available in pharmaceutical-grade and feed-grade specifications, with purity typically confirmed against reference standards by HPLC. Packaging ranges from small quantities for R&D use to bulk quantities.
Industrial formulation requirements are met through various supply options. Quality is maintained through rigorous testing to ensure the material meets the necessary performance criteria for global distribution.
Physical Properties
| Melting Point | 145-147 °C |
| Density | 1.250 g/cm³ |
| Color | Yellow |
| Form | Solid |
Trade & Regulatory
| HS Code | 2934.99.4400 |
Documentation
Other Names
Vitamin B2 tetrabutyrate|riboflavin butyrate|Hibon|Riboflavin 2',3',4',5'-tetrabutyrate|F211C9MSGY|Bituvitan|Lacflavin|Riboflavin, 2′,3′,4′,5′-tetrabutanoate
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