Vitamin B2 Riboflavin Tetrabutyrate

Riboflavin tetrabutyrate (CAS 752-56-7), also known as Vitamin B2 tetrabutyrate and marketed as Hibon, is a lipophilic ester form of riboflavin developed to overcome poor oil solubility.

Where is Vitamin B2 Riboflavin Tetrabutyrate used?

• Pharmaceutical and nutraceutical manufacturing: oil-based capsule formulations and lipid delivery systems
• Feed premixes: fortification of fat-soluble vitamin blends for livestock and aquaculture
• Food: antioxidant and stabilizer in fat-containing matrices such as edible oils and fat-based spreads
• Cosmetics: oil-phase systems for topical applications
• It remains stable through pelleting and extrusion processes.

Good to know: Its fat-soluble profile suits formulations where conventional riboflavin cannot be incorporated; useful where enhanced bioavailability of B2 is a formulation objective.

Commercial specifications

• Purity typically confirmed against reference standards by HPLC
• Packaging from small R&D quantities to bulk