Amines
REACH
Hexamethylenediamine
CAS Number
124-09-4
EC Number
204-679-6
Abbreviation
HMDA
What is Hexamethylenediamine?
Hexamethylenediamine (CAS 124-09-4), abbreviated HMDA, is a primary diamine monomer central to polyamide resins and polymer intermediates.
Where is Hexamethylenediamine used?
- Polymer chemistry and coatings: difunctional building block and crosslinking agent
- Nylon 6,6: principal monomer reacting with adipic acid to form the salt precursor for fiber, film and engineering plastics
- Coatings and adhesives: curing agent for epoxy systems
- Industrial finishes: improves crosslink density and chemical resistance
- Polyurethane and polyurea: HMDA-derived intermediates control chain extension and mechanical performance in elastomers and sealants
- Personal care formulators apply it in limited concentrations for pH adjustment in rinse-off products.
Commercial specifications
- Purity specifications typically 99%+ for monomer-grade material
- Solid flake or crystalline form for smaller-volume packaging
Other Names (Synonyms)
HMDA|HEX-NH2|H2N(CH2)6NH2|1,6-hexylenediamine|1,6-hexanediamine|1,6-hexamethylenediamine|1,6-diaminohexane|1,6-diamino-n-hexane
What are the physical properties of Hexamethylenediamine?
Melting Point 42 °C
Boiling Point 205 °C
Density 0.93 g/cm³
Flash Point 201 °F
Appearance HMDA is a hygroscopic, colorless solid (pellets or flakes). Weak, fishy odor.
Color White, may discolor during storage
Odor pyridine odor
Form Solution
Water Solubility 490 g/L (20 ºC)
Vapor Pressure 0.25 hPa (20 °C)
Refractive Index n 20/D 1.439(lit.)
pH 12.4 (100g/l, H2O, 25℃)
Log P 0.4 at 25℃
How is Hexamethylenediamine classified and handled safely? Learn More
Danger
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
Which trade and regulatory codes apply to Hexamethylenediamine?
HS Code 29212290
UN Number 2735
ADR Class 8
Packing Group III
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 3