n-acetylneuraminic acid

CAS Number
131-48-6
EC Number
205-023-1
Abbreviation
Neu5Ac

What is n-acetylneuraminic acid?

N-Acetylneuraminic acid (CAS 131-48-6), also known as NeuAc, Neu5Ac and NANA, is the predominant sialic acid found in mammalian biology.

Where is n-acetylneuraminic acid used?

  • Pharmaceutical and biotechnology manufacturing: key substrate
  • Analytical reference for sialylation studies, glycoprotein characterization and enzyme assay development
  • Cosmetics: moisture-retention ingredient in skincare
  • Food and nutrition: bioactive ingredient in infant formula and functional foods for cognitive and immune health
  • Biotechnology: precursor in synthesis of sialylated oligosaccharides and therapeutic glycoconjugates
  • It supports skin barrier function at the cellular level.

Commercial specifications

  • Research-grade and high-purity pharmaceutical-grade specifications
  • Purity typically 95% or above
  • GMP-compliant material available for regulated applications
  • Packaging from small laboratory quantities to bulk orders

Other Names (Synonyms)

NeuAc|Neu5Ac|NANA|N-acetyl-beta-neuraminic acid|beta-Neu5Ac|TIP79W5HPN|N-acetyl-beta-D-neuraminic acid|GlyTouCan:G76571JT

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What are the physical properties of n-acetylneuraminic acid?

Melting Point 182-184 °C
Boiling Point 449.56°C (rough estimate)
Density 1.3580 (rough estimate)
Appearance Crystalline
Color White to Off-White
Form synthetic, crystalline
Water Solubility 50 g/L (20 ºC)
Refractive Index -32 ° (C=1, H2O)
Log P -1.897 (est)

How is n-acetylneuraminic acid classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H319 H319

Precautionary Statements

P280 P280
P264+P265 P264+P265
P337+P317 P337+P317
P305+P351+P338 P305+P351+P338

Which trade and regulatory codes apply to n-acetylneuraminic acid?

HS Code 29329900
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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