n-acetylneuraminic acid

N-Acetylneuraminic acid (CAS 131-48-6), commercially recognized under the abbreviations NeuAc, Neu5Ac, and NANA, is the predominant sialic acid found in mammalian biology. It is a critical building block in glycan chemistry. It functions as a bioactive reference compound, surface modification agent, and functional ingredient across pharmaceutical, cosmetic, and biotechnology supply chains. In pharmaceutical and biotech manufacturing, Neu5Ac serves as a key substrate.

It is used as an analytical reference for sialylation studies, glycoprotein characterization, and enzyme assay development. Cosmetic formulators incorporate it into premium skincare products for its moisture-retention properties. It plays a vital role in supporting skin barrier function at the cellular level. In food and nutrition, it is used as a bioactive ingredient in infant formula and functional food products targeting cognitive and immune health.

Biotechnology applications include its use as a precursor in the enzymatic or chemical synthesis of sialylated oligosaccharides and therapeutic glycoconjugates. This versatile compound is essential for modern research. N-Acetylneuraminic acid is supplied as a white to off-white crystalline powder. It is available in research-grade and high-purity pharmaceutical-grade specifications, with purity levels typically at 95% or above.

GMP-compliant material is available for regulated applications. Packaging ranges from small laboratory quantities to bulk orders suited for industrial formulation and large-scale manufacturing needs.