Povidone-iodine
Description
Povidone-iodine (CAS 25655-41-8), commonly abbreviated as PVP-I, is a stable iodine complex used as a broad-spectrum antimicrobial active in pharmaceutical and personal care manufacturing.
Unlike free iodine, it releases active iodine in a controlled manner, making it suitable for formulations requiring sustained efficacy with reduced irritation for various medical applications.
In pharmaceutical manufacturing, PVP-I is the active ingredient in surgical scrubs, wound care solutions, and pre-operative skin antiseptics. Topical antiseptic creams and gels rely on it for infection control.
Personal care formulators incorporate it into antiseptic mouthwashes, throat sprays, and medicated skin cleansers where regulatory-grade antimicrobial performance is required for consumer safety and health.
In food processing environments, it is used in surface disinfection and equipment sanitization protocols where iodine-based biocides are specified to maintain high hygiene standards during production.
Povidone-iodine is supplied as a dark brown powder or as aqueous solutions at standardized iodine concentrations. Recognized grades include USP, BP, and Ph. Eur. for global compliance.
Iodine content and available iodine specifications are defined within each pharmacopoeia. Buyers should confirm the available iodine percentage and polymer molecular weight range for their specific needs.
Both factors affect formulation performance and regulatory compliance. Ensuring these standards are met is critical for the successful manufacturing of high-quality antimicrobial products in the industry.
Physical Properties
| Melting Point | 300 °C |
| Appearance | yellowish to reddish-brown powder |
| Color | Yellow-brown |
| Odor | ylsh. brn. amorphous powd., sl. char. odor |
| Form | Powder |
| Water Solubility | Soluble in water, ethyl alcohol, isopropyl alcohol, polyethylene glycol and glycerol. Insoluble in chloroform, carbon tetrachloride, hexane, acetone and petroleum ether. |
Trade & Regulatory
| HS Code | 29339900 |
| WGK (Germany) | 2 |
Documentation
Other Names
PVP-I|polyvinylpyrrolidone-iodine|E-Z Scrub 241|E-Z Scrub 201|E-Z scrub|E-Z Prep 220|E-Z Prep|Betadine
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