Acetamide
CAS Number
60-35-5
EC Number
200-473-5
What is Acetamide?
Acetamide (CAS 60-35-5), also known as acetic acid amide, is the simplest aliphatic amide; it functions as a solvent, plasticizer and chemical intermediate.
Where is Acetamide used?
- Pharmaceutical manufacturing: reaction intermediate and catalyst precursor in API synthesis
- Personal care: humectant and surface-modifying agent in skin conditioning products
- Biotechnology: buffering component and nitrogen source in microbial culture media and biochemical assays
- Specialty chemical synthesis: catalyst precursor and pH-regulating agent
- Flavoring: FEMA 4251, building block for amide-based compounds
- It serves as a solvent and plasticizer.
Commercial specifications
- Purity: 98% to 99%+
- Packaging: laboratory quantities to bulk industrial supply
Other Names (Synonyms)
Acetic acid amide|Acetimidic acid|Ethanimidic acid|Amid kyseliny octove|NCI-C02108|CH3CONH2
What are the physical properties of Acetamide?
Melting Point 81 °C
Boiling Point 222 °C @ Press: 760 Torr
Density 1.159 g/cm³ @ Temp: 20 °C
Flash Point 220-222°C
Appearance Acetamide is a colorless to yellow, deliquescent, crystalline solid. Odorless if pure, “mousy” odor if impure. Odor threshold5140 160 milligram per cubic meter.
Color White
Odor Mousy odor
Form Crystals
Water Solubility 2000 g/L (20 ºC)
Vapor Pressure 1 mm Hg ( 65 °C)
Refractive Index 1.4274
Log P -1.26
How is Acetamide classified and handled safely? Learn More
Warning
GHS08· Health Hazard
Hazard Statements
H316 Causes mild skin irritation
H320 Causes eye irritation
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
Which trade and regulatory codes apply to Acetamide?
HS Code 29241900
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 11 - Combustible Solids
WGK (Germany) 1