Acetic anhydride

Acetic anhydride (CAS 108-24-7) is a high-volume acetylating agent used in chemical manufacturing to introduce acetyl groups into organic compounds.

Where is Acetic anhydride used?

• Pharmaceuticals: intermediate in aspirin, acetaminophen and cellulose acetate-based excipients
• Textile and paper: acetylating cellulose into acetate fibers and coatings with improved dimensional stability
• Agrochemicals: synthesis of herbicide and pesticide active ingredients requiring acetylation
• Plastics: acetylation of polyvinyl alcohol into polyvinyl acetate and related polymer intermediates
• It also acts as a reactive intermediate and solvent in synthesis processes.
• Production of dyes.
• Production of explosives.
• Acetylating or dehydrating agent in the manufacture of perfumes.
• Esterifying agent for food starch.

Good to know: Pharmaceutical-grade material meeting USP and BP specifications is available for regulated manufacturing environments.

Formulation notes

• Attacks many metals and plastics.

Typical specification

• Specific gravity of 1.08 at 20°C/20°C.
• Flash point of 49°C (closed cup).
• Minimum assay of 97 wt %.

Regulatory status

• For transport, UN Class 8, subsidiary hazard Class 3, packing group II.
• Classified as a flammable liquid and vapour (H226).
• EU index number 607-008-00-9.
• Classified as harmful if inhaled under CLP.

Storage, packaging and handling

• Reacts violently with strong reducing agents, oxidants, strong bases, and water, creating fire and explosion hazards.
• Store only in its original container, separated from food, feed and incompatible materials, fireproof and dry.

Frequently asked questions about Acetic anhydride

What is the occupational exposure limit for acetic anhydride in Germany?

The MAK value is 0.42 mg/m³ (0.1 ppm), with peak limitation category I(2) and pregnancy risk group C.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.