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Acetic anhydride

CAS
108-24-7
EC
200-419-0
Mol. Weight
102.09 g/mol

Description

Acetic anhydride (CAS 108-24-7) is a high-volume acetylating agent used across chemical manufacturing to introduce acetyl groups into organic compounds. It functions as both a reactive intermediate and a solvent in synthesis processes.

In pharmaceuticals, it is a critical intermediate in the production of aspirin, acetaminophen, and various cellulose acetate-based excipients. The textile and paper industries rely on it for acetylating cellulose.

This process produces cellulose acetate fibers and coatings with improved dimensional stability. In agrochemical manufacturing, it serves in the synthesis of herbicide and pesticide active ingredients requiring acetylation steps.

Plastics producers use it to initiate acetylation of polyvinyl alcohol, yielding polyvinyl acetate and related polymer intermediates. Acetic anhydride is supplied as a clear liquid in bulk quantities for industrial procurement.

Available packaging includes ISO tank, drum, and IBC formats suited to large-scale operations. Technical grade is the standard offering for most industrial synthesis and chemical manufacturing applications.

Pharmaceutical-grade material meeting USP and BP specifications is available for regulated manufacturing environments. These grades ensure the purity documentation and traceability required for compliance.

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Safety & Handling (Learn More)

Danger GHS02 GHS05 GHS07 GHS06 GHS08
Hazard Statements
H226 Flammable liquid and vapor [Warning Flammable liquids]
H302 Harmful if swallowed [Warning Acute toxicity, oral]
H314 Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H332 Harmful if inhaled [Warning Acute toxicity, inhalation]
H290 May be corrosive to metals [Warning Corrosive to Metals]
H318 Causes serious eye damage [Danger Serious eye damage/eye irritation]
H331 Toxic if inhaled [Danger Acute toxicity, inhalation]
H370 Causes damage to organs [Danger Specific target organ toxicity, single exposure]
H372 Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
H402 Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]
H313 May be harmful in contact with skin [Warning Acute toxicity, dermal]
H336 May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]
H330 Fatal if inhaled [Danger Acute toxicity, inhalation]

Documentation

Other Names

ethanoic anhydride|ethanoic anhydrate|acetyl oxide|acetyl ether|acetyl anhydride|acetyl acetate|acetic oxide|acetic acid anhydride

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