SoleChem

Methimazole

CAS
60-56-0
EC
200-482-4
Mol. Weight
114.17 g/mol

Description

Methimazole (CAS 60-56-0), also known by the trade name Tapazole and abbreviated as MMI, is an active pharmaceutical ingredient and synthesis intermediate used across pharmaceutical manufacturing and select industrial processes.

It functions as a thyroid hormone synthesis inhibitor in drug formulations and as a stabilizing agent in industrial chemical applications. In pharmaceutical manufacturing, MMI is the active substance in antithyroid drug products.

This makes it a direct procurement target for API suppliers and finished-dose formulators. Textile and leather processors source it as a corrosion inhibitor and stabilizing additive in processing baths where metal ion control is critical.

In paper manufacturing, it is applied as a biocide and preservation agent to extend the service life of process fluids. MMI also serves as a building block in heterocyclic synthesis for chemical production.

Its reactive thione group supports the production of more complex pharmaceutical intermediates. Methimazole is supplied as a white crystalline powder in bulk quantities suited to both pharmaceutical and industrial procurement.

Pharmaceutical-grade material is available to USP and BP specifications, supporting API and formulation manufacturing requirements. Technical-grade material is available for industrial applications.

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Physical Properties

Melting Point 146-148 °C
Boiling Point 280 °C
Density 1.35 g/cm³
Flash Point 280°C
Appearance White Solid
Color White to slightly cream or pale buff
Form Crystalline Powder
Water Solubility soluble
Refractive Index 1.5000 (estimate)

Safety & Handling (Learn More)

Warning GHS07 GHS08
Hazard Statements
H302 H302
H317 H317
H361 H361
Precautionary Statements
P203 P203
P261 P261
P264 P264
P270 P270
P272 P272
P280 P280
P318 P318
P321 P321
P330 P330
P405 P405
P501 P501
P301+P317 P301+P317
P302+P352 P302+P352
P333+P317 P333+P317
P362+P364 P362+P364

Trade & Regulatory

HS Code 29332990
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

1-methylimidazole-2(3H)-thione|1-methyl-1,3-dihydro-2H-imidazole-2-thione|Tapazole|1-Methyl-1H-imidazole-2-thiol|1-Methylimidazole-2-thiol|Mercazole|Thiamazol|2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-|MMI

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