Methimazole

CAS Number
60-56-0
EC Number
200-482-4
Chemical Formula
C4H6N2S
Molecular Weight
114.17 g/mol
Abbreviation
MMI

Description

Methimazole (CAS 60-56-0), also known by the trade name Tapazole and abbreviated as MMI, is an active pharmaceutical ingredient and synthesis intermediate used across pharmaceutical manufacturing and select industrial processes. It functions as a thyroid hormone synthesis inhibitor in drug formulations and as a stabilizing agent in industrial chemical applications. In pharmaceutical manufacturing, MMI is the active substance in antithyroid drug products.

This makes it a direct procurement target for API suppliers and finished-dose formulators. Textile and leather processors source it as a corrosion inhibitor and stabilizing additive in processing baths where metal ion control is critical. In paper manufacturing, it is applied as a biocide and preservation agent to extend the service life of process fluids. MMI also serves as a building block in heterocyclic synthesis for chemical production.

Its reactive thione group supports the production of more complex pharmaceutical intermediates. Methimazole is supplied as a white crystalline powder in bulk quantities suited to both pharmaceutical and industrial procurement. Pharmaceutical-grade material is available to USP and BP specifications, supporting API and formulation manufacturing requirements. Technical-grade material is available for industrial applications.

Other Names (Synonyms)

1-methylimidazole-2(3H)-thione|1-methyl-1,3-dihydro-2H-imidazole-2-thione|Tapazole|1-Methyl-1H-imidazole-2-thiol|1-Methylimidazole-2-thiol|Mercazole|Thiamazol|2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-|MMI

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 146-148 °C
Boiling Point 280 °C
Density 1.35 g/cm³
Flash Point 280°C
Appearance White Solid
Color White to slightly cream or pale buff
Form Crystalline Powder
Water Solubility soluble
Refractive Index 1.5000 (estimate)

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 H302
H317 H317
H361 H361

Precautionary Statements

P203 P203
P261 P261
P264 P264
P270 P270

Trade & Regulatory

HS Code 29332990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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