Coenzyme a
CAS Number
85-61-0
EC Number
201-619-0
Abbreviation
CoA
What is Coenzyme a?
Coenzyme A (CAS 85-61-0), abbreviated CoA, CoASH or HSCoA, is a cofactor involved in acyl group transfer reactions in metabolic pathways.
Where is Coenzyme a used?
- Biochemical reagent for enzymatic synthesis, assay development and acylated intermediates
- Pharmaceutical manufacturing: acetyl-CoA-dependent intermediates for API development and metabolic pathway research
- Biotechnology and life sciences: in vitro enzyme activity assays, coenzyme-dependent reaction screening and metabolic flux studies
- Cosmetic formulators incorporate CoA-based systems into skin care actives targeting cellular energy metabolism and moisture retention.
- Diagnostic kit manufacturing: reference standard and substrate
Good to know: Specifications are typically defined by enzymatic activity rather than conventional chemical purity alone. Consistent purity and activity are procurement-critical for quality control.
Commercial specifications
- Free acid and lithium salt variants
- Research-grade and high-purity biochemical-grade material
Other Names (Synonyms)
HSCoA|CoASH|CoA|Zeel|SAA04E81UX|3'-phosphoadenosine-(5')diphospho(4')pantatheine|Reduced CoA|Thiol-CoA
What are the physical properties of Coenzyme a?
Density 1.96±0.1 g/cm3(Predicted)
Appearance yellowish lyophilisate
Color White to light yellow
Form A crystalline solid
Log P -4.358 (est)
How is Coenzyme a classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
Which trade and regulatory codes apply to Coenzyme a?
HS Code 2933299090
Storage Class 11 - Combustible Solids
WGK (Germany) 3