Allantoin
Description
Allantoin (CAS 97-59-6) is a naturally derived heterocyclic compound used across pharmaceutical and personal care manufacturing. Known commercially as Septalan, Sebical, and Psoralon, it functions as a skin-conditioning agent.
It acts as a keratolytic agent, promoting cell renewal and tissue repair in topical formulations. In pharmaceutical topical preparations, it is incorporated into wound-healing creams and ointments.
Dermatological treatments utilize this compound where it accelerates epithelial regeneration. Personal care manufacturers use it in moisturizers, anti-aging serums, and after-sun products to soothe skin.
Shampoos and scalp treatments rely on this ingredient to condition the scalp and reduce flaking. It is a staple in medicated hair care lines and appears in lip care products and baby formulations.
Mildness and skin tolerance are primary formulation requirements for these sensitive applications. The material is supplied as a white crystalline powder, the standard physical form across all grades.
Pharmaceutical-grade material is available to USP, BP, and Ph.Eur. specifications. These grades meet the purity requirements of regulated drug product manufacturers globally.
Cosmetic-grade material is also widely offered and is the predominant grade used in personal care formulation. It remains a versatile and essential component for modern dermatological and cosmetic science.
Physical Properties
| Melting Point | 239 °C |
| Boiling Point | 478 °C |
| Density | 1.6031 (rough estimate) |
| Flash Point | 230-234°C |
| Appearance | White Solid |
| Color | White |
| Odor | odorless, tasteless |
| Form | Powder |
| Water Solubility | Slightly soluble in water. Freely soluble in alkalis |
| Refractive Index | 1.8500 (estimate) |
| Log P | -2.26 at 20℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29332100 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Documentation
Other Names
Septalan|Sebical|Psoralon|N-(2,5-Dioxo-4-imidazolidinyl)urea|Glyoxylic diureide|Fancol TOIN|D00121|AVC/Dienestrolcream
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