Mannitol

Mannitol (CAS 69-65-8), also known as E421, is a sugar alcohol sourced primarily from natural origins and used in food, pharmaceutical, and personal care manufacturing.

Where is Mannitol used?

• Food: low-calorie bulk sweetener, humectant, and excipient
• Pharmaceuticals: filler and diluent for tablets and capsules in direct compression and freeze-drying
• Confectionery and chewing gum: dusting agent and sweetener that resists sticking and delivers a cooling mouthfeel
• Parenteral formulations: osmotic agent in intravenous solutions for tonicity control
• Personal care: humectant and chelating agent in skincare formulations
• It provides a stable texture in various food products.

Good to know: Non-hygroscopic character in solid dosage forms and clean, mild sweetness in food applications. Granulated forms are often preferred for direct compression tableting.

Commercial specifications

• USP, BP, Ph. Eur., and FCC quality standards
• Bulk quantities standard; smaller packaging for specialty or R&D applications