D-mannose

CAS Number
3458-28-4
EC Number
222-392-4

What is D-mannose?

D-Mannose (CAS 3458-28-4), also sold under the name Demannose, is a naturally occurring monosaccharide sourced primarily from plant materials such as cranberries and birch trees.

Where is D-mannose used?

  • Dietary supplements and functional foods: capsules, tablets and powders targeting urinary tract health
  • Food and beverage: low-glycemic sweetener and nutrient additive in health-oriented products
  • Personal care: humectant in skin creams, serums and hair care products
  • Pharmaceutical manufacturers use it as an excipient and active ingredient in specialized medical nutrition.

Good to know: Pharmaceutical-grade material meets stricter purity thresholds relevant to supplement and drug product manufacturing.

Commercial specifications

  • USP and FCC standards
  • High-purity grades typically exceed 98% assay
  • Bulk supply in kilogram and metric ton quantities

Other Names (Synonyms)

Mannose|(2S,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal|Demannose|PHA4727WTP|CERC-802|GlyTouCan:G95531HX|RefChem:1083138|G95531HX

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What are the physical properties of D-mannose?

Melting Point 132 °C (decomp)
Boiling Point 232.96°C (rough estimate)
Density 1.554 g/cm³ @ Temp: -5 °C
Appearance White crystalline powder
Color White
Form powder
Water Solubility 2480 g/L (17 ºC)
Refractive Index 1.5730 (estimate)
Log P -2.71 at 25℃

Which trade and regulatory codes apply to D-mannose?

HS Code 29400010
WGK (Germany) 3
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