Riboflavine monophosphate
Description
Riboflavine monophosphate (CAS 146-17-8), also known as Flavin mononucleotide (FMN) and designated E101a in food regulation, is the phosphorylated, water-soluble form of riboflavin used as a colorant and nutrient source.
Its superior solubility compared to riboflavin base makes it the preferred choice where consistent color performance and bioavailability in aqueous systems are required across food, pharmaceutical, and biotechnology applications.
In food and beverage manufacturing, E101a delivers a stable yellow-orange hue to liquid products such as soft drinks, dairy alternatives, and sauces where riboflavin's limited solubility would otherwise cause dispersion issues.
Pharmaceutical formulators incorporate FMN into injectable vitamin preparations and oral supplements where a water-soluble B2 source is required for both nutrient delivery and regulatory compliance.
In clinical nutrition, it is used in parenteral and enteral formulations where precise dosing of bioavailable riboflavin is critical for patient health and therapeutic outcomes in medical settings.
Biotechnology applications include its use as a coenzyme source in cell culture media and enzymatic assay systems, supporting growth and metabolic functions in various laboratory and industrial processes.
Riboflavine monophosphate is supplied as a sodium salt in powder form, which is the commercially standard presentation for both food and pharmaceutical procurement and distribution channels.
Food-grade and pharmaceutical-grade material is available, with pharmaceutical supply typically conforming to USP or Ph. Eur. specifications. Purity levels of 98% and above are standard for regulated-market supply.
Physical Properties
| Melting Point | 195 °C |
| Density | 1.83±0.1 g/cm3(Predicted) |
| Appearance | Yellow Crystalline Solid |
| Color | Dark Yellow to Dark Orange |
| Form | Solid |
| Log P | -1.747 (est) |
Documentation
Other Names
Riboflavin 5'-phosphate|[(2r,3s,4s)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] dihydrogen phosphate|Flavin mononucleotide|E101a
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