Trehalose dihydrate

CAS Number
6138-23-4
EC Number
202-739-6
Chemical Formula
C12H22O11.2H2O
Molecular Weight
378.33 g/mol
FEMA Number
FEMA 4600

Description

Trehalose dihydrate (CAS 6138-23-4) is a naturally occurring disaccharide sugar supplied in its stable, crystalline hydrated form. Known commercially as D-(+)-Trehalose dihydrate, it functions as a humectant, cryoprotectant, and stabilizer across food, pharmaceutical, and personal care manufacturing. In food production, it protects flavor compounds, reduces moisture migration in baked goods, and suppresses starch retrogradation to extend shelf life. Pharmaceutical and biotech manufacturers use it to stabilize proteins, vaccines, and lyophilized biologics during freeze-drying processes.

Its cryoprotective properties preserve molecular integrity during these sensitive industrial procedures. In personal care formulations, it retains moisture in skin creams, serums, and lip products while supporting antioxidant stability in sensitive actives. Its mild, clean sweetness also positions it as a functional sugar replacement in confectionery and nutraceutical applications. This is particularly useful where low glycemic impact is a primary formulation priority for the manufacturer.

Trehalose dihydrate is supplied as a white crystalline powder. Food-grade and pharmaceutical-grade specifications are the most commercially available, with pharmaceutical supply typically conforming to USP and Ph.Eur. standards. The material also frequently meets BP and EP requirements, reflecting the ingredient's strong adoption in global manufacturing. Bulk quantities are available for industrial processing, with smaller packaging options for laboratory use.

Specialty formulation use is supported by high-purity batches that meet FCC and ACS quality standards. This ensures consistency and safety across diverse applications in the chemical and life sciences sectors.

Other Names (Synonyms)

alpha-D-Glucopyranoside, alpha-D-glucopyranosyl, dihydrate|RefChem:898940|D-(+)-Trehalose dihydrate|alpha,alpha-Trehalose dihydrate|α-D-Glucopyranoside, α-D-glucopyranosyl, hydrate (1:2)|α-D-Glucopyranoside, α-D-glucopyranosyl, dihydrate|α-D-Glucopyranosyl α-D-glucopyranoside dihydrate|Mycose

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 97 °C
Boiling Point 115.3 °C
Appearance white to off-white crystalline powder
Color White to Off-White
Form powder
Water Solubility 68.9 g/100 mL (20 ºC)
Refractive Index 181 ° (C=7, H2O)

Trade & Regulatory

HS Code 29400090
Storage Class 11 - Combustible Solids
WGK (Germany) 2

Documentation

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