Trehalose dihydrate
Description
Trehalose dihydrate (CAS 6138-23-4) is a naturally occurring disaccharide sugar supplied in its stable, crystalline hydrated form. Known commercially as D-(+)-Trehalose dihydrate, it functions as a humectant, cryoprotectant, and stabilizer across food, pharmaceutical, and personal care manufacturing.
In food production, it protects flavor compounds, reduces moisture migration in baked goods, and suppresses starch retrogradation to extend shelf life. Pharmaceutical and biotech manufacturers use it to stabilize proteins, vaccines, and lyophilized biologics during freeze-drying processes.
Its cryoprotective properties preserve molecular integrity during these sensitive industrial procedures. In personal care formulations, it retains moisture in skin creams, serums, and lip products while supporting antioxidant stability in sensitive actives.
Its mild, clean sweetness also positions it as a functional sugar replacement in confectionery and nutraceutical applications. This is particularly useful where low glycemic impact is a primary formulation priority for the manufacturer.
Trehalose dihydrate is supplied as a white crystalline powder. Food-grade and pharmaceutical-grade specifications are the most commercially available, with pharmaceutical supply typically conforming to USP and Ph.Eur. standards.
The material also frequently meets BP and EP requirements, reflecting the ingredient's strong adoption in global manufacturing. Bulk quantities are available for industrial processing, with smaller packaging options for laboratory use.
Specialty formulation use is supported by high-purity batches that meet FCC and ACS quality standards. This ensures consistency and safety across diverse applications in the chemical and life sciences sectors.
Physical Properties
| Melting Point | 97 °C |
| Boiling Point | 115.3 °C |
| Appearance | white to off-white crystalline powder |
| Color | White to Off-White |
| Form | powder |
| Water Solubility | 68.9 g/100 mL (20 ºC) |
| Refractive Index | 181 ° (C=7, H2O) |
Trade & Regulatory
| HS Code | 29400090 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Documentation
Other Names
alpha-D-Glucopyranoside, alpha-D-glucopyranosyl, dihydrate|RefChem:898940|D-(+)-Trehalose dihydrate|alpha,alpha-Trehalose dihydrate|α-D-Glucopyranoside, α-D-glucopyranosyl, hydrate (1:2)|α-D-Glucopyranoside, α-D-glucopyranosyl, dihydrate|α-D-Glucopyranosyl α-D-glucopyranoside dihydrate|Mycose
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