Cellulose acetate phthalate

CAS Number
9004-38-0
EC Number
618-382-8

What is Cellulose acetate phthalate?

Cellulose acetate phthalate (CAS 9004-38-0), commonly abbreviated as CAP, is a cellulose-derived polymer ester used primarily as an enteric coating agent in pharmaceutical manufacturing.

Where is Cellulose acetate phthalate used?

  • Oral dosage forms: controls release by remaining intact in gastric acid and dissolving at higher intestinal pH
  • Enteric coating of tablets
  • Capsules and granules: protection from stomach acid for acid-sensitive active pharmaceutical ingredients
  • Sustained-release pellet systems: coating thickness and polymer concentration determine dissolution lag time
  • Film-coating solutions: incorporated with plasticizers for coating uniformity
  • Controlled-release granulation: binder and matrix former

Commercial specifications

  • Pharmaceutical-grade specifications meeting USP and Ph. Eur. standards
  • Fiber drum or multi-wall bag packaging suited to GMP production environments and large scale logistics

Other Names (Synonyms)

Cellulose, acetate hydrogen 1,2-benzenedicarboxylate|RefChem:124308|NCGC00188441-01|Cellulose, acetate hydrogen phthalate|Phthalic acid, ester with cellulose acetate|Cellulose acetate-phthalate mixed ester|Cellulose acetophthalate

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What are the physical properties of Cellulose acetate phthalate?

Appearance white granular powder
Form neat

How is Cellulose acetate phthalate classified and handled safely? Learn More

Warning
GHS02· Flammable GHS07· Irritant

Hazard Statements

H252 Self-heating in large quantities; may catch fire
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P235 Keep cool.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Cellulose acetate phthalate?

HS Code 39129010
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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