Flavors & Fragrances
REACH
L-menthol
CAS Number
2216-51-5
EC Number
218-690-9
FEMA Number
FEMA 2665
What is L-menthol?
L-menthol (CAS 2216-51-5), also known as peppermint camphor, is the naturally occurring enantiomer of menthol derived primarily from peppermint oil or produced synthetically.
Where is L-menthol used?
- Pharmaceuticals: topical analgesics, cough suppressants, throat lozenges
- Food and beverage: flavoring agent in confectionery, chewing gum, oral care products
- Personal care: toothpastes, shaving gels, cooling skincare products
- Tobacco manufacturers source it as a primary component.
Good to know: Natural and synthetic grades are commercially available; natural origin material commands a premium where botanical sourcing is required.
Other Names (Synonyms)
peppermint camphor|5-methyl-2-propan-2-ylcyclohexan-1-ol|5-methyl-2-(1-methylethyl)cyclohexanol|2-isopropyl-5-methylcyclohexanol|1-menthol|[1R-(1-alpha,2-beta,5-alpha)]-5-methyl-2-(1-methylethyl)cyclohexanol|(R)-(-)-menthol|(1R)-(-)-menthol
What are the physical properties of L-menthol?
Melting Point 41-43 °C
Boiling Point 212 °C
Density 0.890 g/cm³
Flash Point 200 °F
Appearance white to light yellow crystal powde
Color Colorless to white
Odor at 10.00 % in dipropylene glycol. peppermint cooling mentholic minty
Form Crystals or Crystalline Needles
Water Solubility insoluble
Vapor Pressure 0.8 mm Hg ( 20 °C)
Refractive Index 1.46
Log P 3.15 at 25℃
How is L-menthol classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H320 Causes eye irritation
H336 May cause drowsiness or dizziness
H402 Harmful to aquatic life
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
Which trade and regulatory codes apply to L-menthol?
HS Code 29061100
Storage Class 11 - Combustible Solids
WGK (Germany) 2