Hydroxocobalamin Acetate

CAS Number
22465-48-1
EC Number
245-019-7

What is Hydroxocobalamin Acetate?

Hydroxocobalamin Acetate (CAS 22465-48-1) is a naturally occurring form of Vitamin B12; a crystalline powder of approximately 1,388 g/mol.

Where is Hydroxocobalamin Acetate used?

  • Pharmaceutical and API manufacturing: produced and tested to USP and Ph. Eur. standards for injectable preparations, parenteral formulations and prescription-grade supplements
  • Nutraceutical and dietary supplements: Vitamin B12 with authorised EU health claims under Regulation (EC) No 432/2012
  • Personal care and cosmetics: antioxidant and stabiliser in serums, ampoules and topical preparations
  • It is compatible with aqueous systems for water-based cosmetic matrices.

Good to know: Hydroxocobalamin Acetate is not listed in Annex II of Directive 2002/46/EC; verify regulatory suitability for finished supplement labelling with your compliance team. It is sparingly soluble in water, alcohol and methanol, a handling consideration for premix preparation and dissolution protocols.

Commercial specifications

  • Purity typically 99% or above
  • Pharmaceutical-grade and cosmetic-grade specifications
  • Packaging: 1–5 kg units and 25 kg drums; custom pack sizes available
  • Storage: sealed, away from moisture and light, at controlled low temperature

Other Names (Synonyms)

twelvmin|fresmins|Novidroxin|acetato-cobalami|acetatocobalamin|VITAMIN B12A ACETATE|YDROXOCOBALAMIN ACETATE

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What are the physical properties of Hydroxocobalamin Acetate?

Melting Point >3000C.
Log P -2.812 (est)
Appearance Dark-Red Crystalline Powder
Color Dark Red
Form Solid

How is Hydroxocobalamin Acetate classified and handled safely? Learn More

Warning
GHS08· Health Hazard

Hazard Statements

H351 Suspected of causing cancer
H373 May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
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