Potassium gluconate

Potassium gluconate (CAS 299-27-4), also known by its food additive designation E577, is a potassium mineral salt used across food, pharmaceutical, and personal care manufacturing.

Where is Potassium gluconate used?

• Dietary supplements and functional foods: bioavailable potassium for electrolyte and mineral fortification in tablets, capsules, and powders
• Food manufacturing: sequestrant and pH buffer that stabilizes formulations
• Pharmaceutical manufacturing: active mineral ingredient in oral rehydration salts and electrolyte preparations
• Personal care: humectant and chelating agent in skin care products
• In cosmetic applications it retains moisture and manages trace metal ions that can destabilize emulsions.
• Used as a buffer salt in foodstuffs where sodium is not desired.
• Used for direct compression in tablet manufacture.
• Used in feed supplements for performance animals for electrolyte balance.

Typical specification

• Easily soluble in water.
• A directly compressible form offers optimal compression properties due to its amorphous structure.
• Potassium content of 17%.

Regulatory status

• Potassium is on the positive list of Regulation (EC) No 1925/2006 on the addition of vitamins and minerals to foods, and its use is authorized in food supplements under Directive 2002/46/EC.
• In Europe, listed as a generally permitted food additive (E577) and may be added to all foods on a quantum satis basis under Regulation (EC) No 1333/2008 (Annex II), unless a specific regulation limits its use.
• Listed as a mineral salt in Regulation (EU) No 609/2013 on foods for infants and young children, foods for special medical purposes and total diet replacement for weight control.

Storage, packaging and handling

• Supplied in anhydrous form with low hygroscopicity.
• Hygroscopic and can absorb moisture from the air, causing caking or clumping if not stored properly.

Frequently asked questions about Potassium gluconate

What grade forms are available on the market?

Potassium gluconate is supplied as anhydrous USP grade.

In which industrial processes is potassium gluconate used as a buffer or stabilizer?

It is used as buffer/stabilizer systems in fermentation processes and as a reference standard in quality control laboratories for HPLC/ICP-MS calibration.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.