Calcium gluconate
Description
Calcium gluconate (CAS 299-28-5), also known by its food additive designation E578, is a calcium salt of gluconic acid used across food, pharmaceutical, and personal care manufacturing.
It functions as a mineral supplement, pH buffer, and chelating agent depending on the application context. In food and beverage production, it acts as a firming agent and acidity regulator.
This ingredient maintains texture in canned vegetables and processed dairy products. Pharmaceutical manufacturers use it as a direct calcium source in oral and injectable mineral supplement formulations.
In personal care, it buffers pH and chelates metal ions in skincare and haircare products. This improves formulation stability and extends shelf life for a wide variety of consumer goods.
Food-grade calcium gluconate also serves as a sequestrant in baking and dairy processing. Controlling free calcium ions in these environments directly affects the final texture and consistency.
The material is supplied as a white crystalline powder or granules. Standard grades include USP, BP, Ph. Eur., and food-grade (FCC) to meet diverse industry requirements.
Pharmaceutical grades meet strict purity thresholds for injectable and oral dosage applications. Packaging typically ranges from 25 kg bags to bulk quantities depending on the intended grade.
Physical Properties
| Melting Point | 120 °C |
| Boiling Point | 400°C[at 101 325 Pa] |
| Density | 1.677[at 20℃] |
| Appearance | white crystalline powder or granules |
| Color | White |
| Odor | at 100.00?%. odorless |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 3.3 g/100mL |
| Vapor Pressure | 0.004Pa at 20℃ |
| pH | pH;6.0~8.0 |
| Log P | -5.31 at 20℃ |
Trade & Regulatory
| HS Code | 38220090 |
| WGK (Germany) | 1 |
Documentation
Other Names
E578|D-gluconic acid, calcium salt (2:1)|D-Gluconic acid calcium salt|Calcium gluconate, anhydrous|Calcium di-gluconate|Calciofon|Calcii gluconas|Calcarea gluconica
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