Copper gluconate

Copper gluconate (CAS 527-09-3) is the copper(II) salt of gluconic acid, a bioavailable source of dietary copper.

Where is Copper gluconate used?

• Nutritional supplements and fortified foods: highly absorbable mineral source
• Tablets, capsules and functional beverages
• Pharmaceutical mineral formulation blends: consistent copper content and solubility for dosage accuracy
• Personal care: stable, water-soluble copper source in anti-aging and skin-conditioning products
• Feed and premix producers supplement copper in livestock and poultry diets to meet mineral inclusion targets.
• In the pharmaceutical industry, its buffer property is used for encapsulating certain drugs into liposomes.
• Used as a copper source in the treatment of anemia and nephrosis.
• Used in food as a synergist.

Good to know: Its chelated structure makes it more stable and easier to incorporate into finished formulations than inorganic copper salts.

Typical specification

• Contains approximately 14.0% copper.
• Solubility in water at 20 °C is greater than 100 g/l.
• A 1% solution has a pH of about 4.
• Offered as a crystalline powder with an assay of 98% to 102%.

Regulatory status

• API documentation (ASMF / DMF) is available for this product.
• Subject to a USP-NF monograph (Monograph Number 20040).
• For pharmaceutical use, it should meet USP, Ph. Eur. or the relevant pharmacopoeia quality grade.
• Regulated as a food additive under 21 CFR 184.1260 in the US.

Frequently asked questions about Copper gluconate

What grades of copper gluconate are available on the market?

Food grade, pharmaceutical grade and cosmetic grade qualities are offered.

Can copper gluconate be used as an excipient in pharmaceutical formulations?

It can be used as an excipient to increase the bioavailability of disulfiram for inhibiting cancer cells.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.