Calcium citrate tetrahydrate

CAS Number
5785-44-4
EC Number
629-915-9

What is Calcium citrate tetrahydrate?

Calcium citrate tetrahydrate (CAS 5785-44-4) is a calcium salt of citric acid used as a mineral supplement, buffering agent and food additive. Also marketed as Calcium Citrate USP.

Where is Calcium citrate tetrahydrate used?

  • Food and beverage: firming agent and acidity regulator
  • Calcium fortification source in juices, dairy alternatives and infant formula
  • Pharmaceuticals: active calcium supplement ingredient and excipient in tablet and powder dosage forms
  • Water treatment: sequestering action controls scale formation and stabilises treatment chemistry
  • Personal care: pH buffer and stabiliser in creams, lotions and oral care products
  • It delivers bioavailable calcium while controlling pH and chelating metal ions.

Good to know: The USP designation is the most commercially prevalent and referenced in pharmaceutical and food industry procurement; the USP-grade specification supports strict compliance requirements for medicinal products.

Commercial specifications

  • Bulk quantities standard for industrial buyers; smaller packaging for formulators and quality control

Other Names (Synonyms)

Calcium citrate (USP)|RefChem:1080678|tricalcium;2-hydroxypropane-1,2,3-tricarboxylate;tetrahydrate|1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt (2:3), tetrahydrate|Calcium 2-hydroxypropane-1,2,3-tricarboxylate tetrahydrate|1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt, hydrate (2:3:4)|Citric acid, calcium salt (2:3), tetrahydrate

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What are the physical properties of Calcium citrate tetrahydrate?

Melting Point >300°C
Appearance White powder
Color Clear
Odor Odorless
Form Liquid
Water Solubility Soluble in water and hydrochloric acid.
pH 5-6 (20°C, 25g/L in H2O, slurry)
Log P -1.721 (est)

How is Calcium citrate tetrahydrate classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Which trade and regulatory codes apply to Calcium citrate tetrahydrate?

HS Code 29181500
Storage Class 11 - Combustible Solids
WGK (Germany) 1
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