Calcium citrate tetrahydrate

CAS Number
5785-44-4
EC Number
629-915-9
Chemical Formula
C6H8O7.3/2Ca.2H2O
Molecular Weight
570.5 g/mol

Description

Calcium citrate tetrahydrate (CAS 5785-44-4) is a calcium salt of citric acid used as a mineral supplement, buffering agent, and food additive across multiple industries. It delivers bioavailable calcium while simultaneously controlling pH and chelating metal ions. Commercially supplied as Calcium Citrate USP, this compound helps prevent the degradation of product quality in various formulations. In food and beverage manufacturing, it functions as a firming agent and acidity regulator.

It is a primary calcium fortification source in products such as juices, dairy alternatives, and infant formula. Pharmaceutical formulators use it as an active calcium supplement ingredient and excipient in tablet and powder dosage forms. The USP-grade specification supports strict compliance requirements for medicinal products. Water treatment applications rely on its sequestering action to control scale formation and stabilize treatment chemistry effectively.

In personal care formulations, it acts as a pH buffer and stabilizer in creams, lotions, and oral care products. Calcium citrate tetrahydrate is supplied as a white powder available in both pharmaceutical and food-grade specifications. The USP designation is the most commercially prevalent and referenced in pharmaceutical and food industry procurement. Bulk quantities are standard for industrial buyers, with smaller packaging available for formulators and quality control purposes.

Other Names (Synonyms)

Calcium citrate (USP)|RefChem:1080678|tricalcium;2-hydroxypropane-1,2,3-tricarboxylate;tetrahydrate|1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt (2:3), tetrahydrate|Calcium 2-hydroxypropane-1,2,3-tricarboxylate tetrahydrate|1,2,3-Propanetricarboxylic acid, 2-hydroxy-, calcium salt, hydrate (2:3:4)|Citric acid, calcium salt (2:3), tetrahydrate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point >300°C
Appearance White powder
Color Clear
Odor Odorless
Form Liquid
Water Solubility Soluble in water and hydrochloric acid.
pH 5-6 (20°C, 25g/L in H2O, slurry)
Log P -1.721 (est)

Safety & Handling (Learn More)

Warning
GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation

Precautionary Statements

P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264+P265 Wash … thoroughly after handling.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29181500
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Documentation

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