Lithium amide

Lithium amide (CAS 7782-89-0), also known as Lithamide, is a strong inorganic base used as a reagent and catalyst in synthetic chemistry.

Where is Lithium amide used?

• Pharmaceutical synthesis: deprotonating agent driving condensation and deprotonation reactions to produce active pharmaceutical intermediates
• Polymer manufacturing: polymerization initiator for anionic polymerization of monomers such as styrene and butadiene, controlling molecular weight distribution in specialty elastomers and resins
• Biotechnology: supports synthesis of complex organic molecules requiring selective nitrogen-based base chemistry
• Specialty chemicals: pH-regulating catalyst where conventional bases would introduce unwanted counterions or side reactions
• It functions as a deprotonating agent and polymerization initiator.

Good to know: Due to its reactivity with moisture, it is handled and packaged under inert atmosphere.

Commercial specifications

• Technical and high-purity grades
• Packaging from small laboratory quantities to bulk quantities