Calcium salicylate

CAS Number
824-35-1
EC Number
212-525-4

What is Calcium salicylate?

Calcium salicylate (CAS 824-35-1), also known as calcium disalicylate, is the calcium salt of salicylic acid.

Where is Calcium salicylate used?

  • Pharmaceutical manufacturing: intermediate in the synthesis of salicylate-based active ingredients
  • Tablet and oral formulation development: buffering component
  • Personal care: preservative and pH-buffering agent in topical preparations
  • Dermatological formulations: evaluated for exfoliation and skin conditioning
  • Compounding pharmacies and specialty chemical manufacturers use it as a starting material for further salt conversions.

Good to know: Often selected where sodium or free-acid forms are unsuitable due to solubility or compatibility constraints; provides benefits without the irritation profile of free salicylic acid.

Commercial specifications

  • Pharmaceutical-grade specifications aligned with USP, BP and EP
  • Packaging from laboratory-scale quantities to bulk industrial supply

Other Names (Synonyms)

Calcium disalicylate|Benzoic acid, 2-hydroxy-, calcium salt (2:1)|0841QCS0DK|RefChem:573557|Salicylic acid, calcium salt (2:1)|Cyl-Re|Helioscin

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What are the physical properties of Calcium salicylate?

Form solid
Log P 2.061 (est)

How is Calcium salicylate classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed [Warning Acute toxicity, oral]

Which trade and regulatory codes apply to Calcium salicylate?

Storage Class 11 - Combustible Solids
WGK (Germany) 3
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