SoleChem

Sumatriptan succinate

CAS
103628-48-4
EC
600-463-4
Mol. Weight
413.5 g/mol

Description

Sumatriptan succinate (CAS 103628-48-4) is the succinate salt form of sumatriptan, a selective serotonin receptor agonist used as the active pharmaceutical ingredient in acute migraine and cluster headache treatments.

The salt form offers improved stability and solubility characteristics that are critical for pharmaceutical dosage form development. The primary application is as an API in prescription migraine therapies.

It is formulated into tablets, nasal sprays, and subcutaneous injection products for rapid symptom relief. Pharmaceutical manufacturers source this compound for solid oral dosage forms where precise particle size is required.

Polymorphic consistency directly affects bioavailability and dissolution performance in these formulations. Contract development organizations use it in reformulation projects targeting modified-release or needle-free delivery platforms.

It is also procured by generic drug manufacturers developing bioequivalent products to reference-listed branded formulations. The material is available as a white to off-white crystalline powder for industrial use.

It is supplied in pharmaceutical-grade specifications conforming to USP and BP monographs. Documentation packages typically include CoA, DMF references, and ICH-compliant impurity profiles.

Packaging is offered in quantities ranging from research-scale grams to commercial kilogram lots. This ensures flexibility for both pilot-scale development and full-scale commercial manufacturing requirements.

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Physical Properties

Melting Point 165-166 °C
Appearance White Crystalline Powder
Color white to off-white
Form solid

Safety & Handling (Learn More)

Danger GHS05 GHS08
Hazard Statements
H318 Causes serious eye damage
H361 Suspected of damaging fertility or the unborn child
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29350090
WGK (Germany) 3

Documentation

Other Names

sumatriptan hydrogen succinate|3-(2-(Dimethylamino)ethyl)-N-methylindole-5-methanesulfonamide succinate|Sumavel DosePro|Alsuma|Onzetra Xsail|Imitrex Statdose|GR 43175C|Zembrace SymTouch

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