Sumatriptan succinate

CAS Number
103628-48-4
EC Number
600-463-4

What is Sumatriptan succinate?

Sumatriptan succinate (CAS 103628-48-4) is the succinate salt form of sumatriptan, a selective serotonin receptor agonist; the active pharmaceutical ingredient in acute migraine and cluster headache treatments.

Where is Sumatriptan succinate used?

  • Prescription migraine therapies: API
  • Tablets, nasal sprays and subcutaneous injections for rapid symptom relief
  • Solid oral dosage forms requiring precise particle size
  • Reformulation projects targeting modified-release or needle-free delivery platforms
  • Generic drug manufacturers develop bioequivalent products to reference-listed branded formulations.

Good to know: Polymorphic consistency directly affects bioavailability and dissolution performance.

Commercial specifications

  • Pharmaceutical-grade specifications conforming to USP and BP monographs
  • Documentation: CoA, DMF references, ICH-compliant impurity profiles
  • Packaging from research-scale grams to commercial kilogram lots

Other Names (Synonyms)

sumatriptan hydrogen succinate|3-(2-(Dimethylamino)ethyl)-N-methylindole-5-methanesulfonamide succinate|Sumavel DosePro|Alsuma|Onzetra Xsail|Imitrex Statdose|GR 43175C|Zembrace SymTouch

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What are the physical properties of Sumatriptan succinate?

Melting Point 165-166 °C
Appearance White Crystalline Powder
Color white to off-white
Form solid

How is Sumatriptan succinate classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS08· Health Hazard

Hazard Statements

H318 Causes serious eye damage
H361 Suspected of damaging fertility or the unborn child
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.

Which trade and regulatory codes apply to Sumatriptan succinate?

HS Code 29350090
WGK (Germany) 3
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