Glutathione

CAS Number
70-18-8
EC Number
200-725-4
Chemical Formula
C10H17N3O6S
Molecular Weight
307.33 g/mol
Abbreviation
GSH

Description

Glutathione (CAS 70-18-8), also known as GSH, is a tripeptide antioxidant produced through fermentation and widely sourced for use across pharmaceutical, food, and cosmetic manufacturing. It functions as a reducing agent and antioxidant stabilizer, protecting formulations and biological systems from oxidative degradation. In pharmaceutical manufacturing, GSH serves as an active ingredient.

It is used in injectables, oral supplements, and lyophilized drug formulations where oxidative stability is critical. Food and beverage producers incorporate it as an antioxidant to extend shelf life. In dough systems, it modifies gluten structure to improve processing performance in baked goods. Cosmetic and personal care formulators use it in skin-brightening serums, creams, and topical products.

These products target uneven skin tone through melanin pathway modulation. In biotechnology, it functions as a critical reagent in cell culture media and protein purification processes. It is particularly useful in refolding disulfide-bonded proteins. This material is supplied as a white to off-white crystalline powder available in pharmaceutical-grade (USP, BP, Ph. Eur.) specifications.

It also meets food-grade (FCC) requirements to satisfy regulatory standards across different end markets. Reduced glutathione is the predominant commercial form for industrial-scale procurement.

Other Names (Synonyms)

Isethion|GSH|Glutinal|Glutide|Glutatiol|Glutathione-SH|Glutathione reduced|Glutathione red

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 195 °C
Boiling Point 754.5±60.0 °C(Predicted)
Density 1.4482 (rough estimate)
Appearance White cryst. powder
Color White
Odor Odorless
Form powder
Water Solubility soluble
Refractive Index -17 ° (C=2, H2O)
pH 3 (10g/l, H2O, 20°C)
Log P -1.645 (est)

Safety & Handling (Learn More)

Warning
GHS08· Health Hazard

Hazard Statements

H341 Suspected of causing genetic defects

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.

Trade & Regulatory

HS Code 29309070
Storage Class 11 - Combustible Solids
WGK (Germany) 2

Documentation

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