Calcium lactobionate

CAS Number
5001-51-4
EC Number
225-668-2

What is Calcium lactobionate?

Calcium lactobionate (CAS 5001-51-4), also identified by E-number E399, is the calcium salt of lactobionic acid.

Where is Calcium lactobionate used?

  • Food and beverage: firming agent and sequestrant that binds trace metals
  • Pharmaceuticals: calcium supplement source and stabilizing excipient in oral and parenteral formulations
  • Cosmetics and skincare: moisture-binding capacity in serums, creams and leave-on treatments
  • Dairy processing: calcium fortification and texture stabilization
  • It functions as a chelating agent, humectant and stabilizer.

Commercial specifications

  • Anhydrous and monohydrate forms
  • USP or Ph. Eur. specifications

Other Names (Synonyms)

calcium lactobionate anhydrous|Lactobionic acid, calcium salt (2:1)|258F856K63|Calcium bis(4-O-(beta-D-galactosyl)-D-gluconate)|D-Gluconic acid, 4-O-beta-D-galactopyranosyl-, calcium salt (2:1)|RefChem:200044|Lactobionic acid calcium salt|E399

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What are the physical properties of Calcium lactobionate?

Melting Point ~190 °C (dec.)
Appearance White powder. Sol in water; insol in alc, ether.
Color White to Almost white
Form powder to crystal
Refractive Index 24 ° (C=6, H2O)
Log P -4.058 (est)

How is Calcium lactobionate classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Calcium lactobionate?

HS Code 2940.00.6000
WGK (Germany) 3
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