L-theanine

CAS Number
3081-61-6
EC Number
221-379-0
Chemical Formula
C7H14N2O3
Molecular Weight
174.20 g/mol

Description

L-Theanine (CAS 3081-61-6), also known as N-Ethyl-L-glutamine, is a naturally occurring amino acid derived primarily from green tea. In commercial formulations, it functions as a bioactive ingredient valued for its calming and focus-supporting properties. This versatile compound is utilized across the nutraceutical, pharmaceutical, and personal care markets. In dietary supplements, it is a primary active ingredient in stress-relief, sleep support, and cognitive performance products.

It is often combined with caffeine in capsule or tablet formats to enhance mental clarity. Food and beverage manufacturers incorporate it into functional drinks, nootropic shots, and fortified snacks targeting relaxation without sedation. Pharmaceutical formulators use it as an excipient with mild buffering capacity and as an active in OTC wellness preparations. In personal care, it is used in moisturizing and antioxidant skincare formulations.

Its unique amino acid structure supports humectancy and skin-conditioning performance in topical applications. L-Theanine is supplied as a white crystalline powder for easy integration into various manufacturing processes. Standard grades include food-grade and USP-compliant specifications, with purity levels typically at 98% or higher. These high standards ensure safety and efficacy for sensitive consumer applications.

Bulk quantities are available for industrial formulation, with smaller packaging options suited to nutraceutical compounding. This flexibility allows for both large-scale production and specialized laboratory use.

Other Names (Synonyms)

(2S)-2-azaniumyl-5-(ethylamino)-5-oxopentanoate|N-Ethyl-L-glutamine|2-Amino-4-(ethylcarbamoyl)butanoic acid|Theanine|Theanin|(2S)-2-amino-5-(ethylamino)-5-oxopentanoic acid|8021PR16QO

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 217-220 °C
Boiling Point 430.2±40.0 °C(Predicted)
Density 1.171±0.06 g/cm3(Predicted)
Appearance White Crystalline Solid
Color White
Odor Odorless
Form powder
Water Solubility almost transparency
Refractive Index 8 ° (C=5, H2O)
Log P -0.661 (est)

Safety & Handling (Learn More)

Warning
GHS07· Irritant

Hazard Statements

H317 H317

Precautionary Statements

P261 P261
P272 P272
P280 P280
P321 P321
P501 P501
P302+P352 P302+P352
P333+P317 P333+P317
P362+P364 P362+P364

Trade & Regulatory

HS Code 29241990

Documentation

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