L-isoleucine
Description
L-Isoleucine (CAS 73-32-5) is an essential branched-chain amino acid that the human body cannot synthesize, making dietary or supplemental sourcing necessary. In industry, it functions as a nutritional active and a fermentation building block.
It also serves as a pharmaceutical excipient or active ingredient across multiple formulation types. In sports nutrition and clinical nutrition, it is formulated into BCAA blends, protein powders, and medical foods targeting muscle metabolism.
Pharmaceutical manufacturers use it as an active ingredient in amino acid infusion solutions and parenteral nutrition products. Precise purity and endotoxin control are critical sourcing criteria for these specific medical applications.
Food and beverage producers incorporate it into functional drinks, meal replacements, and fortified foods to meet amino acid profile requirements. It is also used in cosmetic formulations for skin-conditioning and hair care preparations.
The product is supplied as a white crystalline powder. Standard grades include USP, BP, Ph. Eur., and food-grade (FCC), ensuring compliance with global regulatory requirements for safety and quality.
Pharmaceutical grades are subject to additional specifications for residual solvents and microbial limits. Bulk supply is available in kilogram and metric-ton quantities to serve both industrial formulators and smaller-scale manufacturers.
Physical Properties
| Melting Point | 285.5 °C (decomp) |
| Boiling Point | 225.8±23.0 °C(Predicted) |
| Density | 1.2930 (estimate) |
| Flash Point | 168-170°C |
| Appearance | White crystalline powder |
| Color | White to Off-white |
| Odor | odorless |
| Form | powder |
| Water Solubility | 41.2 g/L (50 ºC) |
| Refractive Index | 40.5 ° (C=4, 6mol/L HCl) |
| pH | 5.5-6.5 (40g/l, H2O, 20℃) |
| Log P | 0.80 |
Trade & Regulatory
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Documentation
Other Names
(2S,3S)-2-azaniumyl-3-methylpentanoate|α-amino-β-methylvaleric acid|L-Ile|alpha-amino-beta-methylvaleric acid|2-Amino-3-methylvaleric acid|(2S,3S)-2-Amino-3-methylpentanoic acid|Ile|2S,3S-Isoleucine
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